基本信息
| 登记号 | CTR20132406 | 试验状态 | 进行中 |
|---|---|---|---|
| 申请人联系人 | 刘蔚 | 首次公示信息日期 | 2015-10-13 |
| 申请人名称 | 百时美施贵宝（中国）投资有限公司/ Bristol-Myers Squibb Company/ Bristol-Myers Squibb | ||
公示的试验信息
一、题目和背景信息
| 登记号 | CTR20132406 | ||
|---|---|---|---|
| 相关登记号 | |||
| 药物名称 | 阿哌沙班(BMS-562247)包膜片5 mg | ||
| 药物类型 | 化学药物 | ||
| 临床申请受理号 | 企业选择不公示 | ||
| 适应症 | 非瓣膜性房颤 | ||
| 试验专业题目 | 比较阿哌沙班与阿司匹林在维生素K拮抗剂治疗失败或不适用的房颤患者中预防卒中的作用 | ||
| 试验通俗题目 | 在Vk拮抗剂治疗失败或不适用的房颤患者中预防卒中研究 | ||
| 试验方案编号 | CV185-048 | 方案最新版本号 | |
| 版本日期: | 方案是否为联合用药 | 企业选择不公示 | |
二、申请人信息
| 申请人名称 | 1 2 3 | ||||
|---|---|---|---|---|---|
| 联系人姓名 | 刘蔚 | 联系人座机 | 021-23218416 | 联系人手机号 | |
| 联系人Email | Kelly.liu@bms.com | 联系人邮政地址 | 上海市南京西路1717号会德丰广场59楼 | 联系人邮编 | 200040 |
三、临床试验信息
1、试验目的
对于患有房颤且至少还有一种卒中危险因素且不适合维生素K拮抗剂治疗或治疗失败的患者，明确阿哌沙班5mg BID（某些特定患者为2.5mg BID[每日二次]）在卒中或体循环栓塞复合事件的预防中是否优于ASA（81 - 324 mg QD[每日一次] ）
2、试验设计
| 试验分类 | 安全性和有效性 | 试验分期 | III期 | 设计类型 | 平行分组 |
|---|---|---|---|---|---|
| 随机化 | 随机化 | 盲法 | 双盲 | 试验范围 | 国际多中心试验 |
3、受试者信息
| 年龄 | 50岁(最小年龄)至 NA岁(最大年龄) | ||
|---|---|---|---|
| 性别 | 男+女 | ||
| 健康受试者 | 无 | ||
| 入选标准 | 1 签署书面知情同意书 2 筛选当日的12导联ECG确认为永久性，阵发性或持续性房颤 3 如果筛选时没有房颤，则必须有在入选前6个月内经12导联ECG记录的房颤，或心律长条图或动态心电图上记录的房颤发作时间至少为5分钟。也可采用起搏器或ICD心电图记录AF，但如果只有这种方式记录到AF，则AF的持续时间必须至少为30分钟。 4 至少存在一种以下卒中危险因素：既往卒中或TIA病史；年龄≥ 75 岁；治疗期间的动脉高血压；糖尿病；心功能衰竭。入选时NYHA分级为2级或2级以上；入选前6个月内记录到的左心室射血分数≤35％ | ||
| 排除标准 | 1 性别和生育状况: a)妊娠或哺乳期妇女;b)不愿遵守研究中妊娠试验要求（见7.6.1 妊娠试验要求）或不愿/不能采取可接受的避孕措施的育龄妇女 (WOCBP) 2 作为排除标准的疾病:a)可逆性原因（如甲状腺中毒症，心包炎）导致的房颤;b)需要手术的瓣膜病变; c)计划在3个月内行房颤消融术 3 病史和伴随疾病:a)除房颤外，其他需要长期使用抗凝药的状态（如机械心脏瓣膜，静脉血栓形成；也见5.5节伴随治疗）; b)过去6个月内有严重出血或有出血高危因素的患者，包括但不限于：活动性消化性溃疡，血小板计数 < 100,000/mm3 或血红蛋白< 10g/dL，最近发作卒中 (过去10 天内)，有记录的出血倾向或血液异常；c)目前的酗酒或药物滥用，或导致无法参加研究的心理社会原因；d)严重的合并症，预期寿命<1年 4 体检和实验室检查结果: a)严重的肾功能不全 (必须计算所有病人的肌酐清除率；任何病人的血肌酐> 2.5 mg/dL [221 umol/L] 或计算的肌酐清除率≤ 25 ml/min必须排除)；b)ALT或AST >正常值上限的2倍或总胆红素>正常值上限的 1.5 倍[除非发现另一种导致这种结果的原因(如Gilbert综合征) ] 5 过敏和药物不良反应:对ASA过敏或有不良反应 6 禁用药物和/或疗法:a)参加研究时禁止使用的药物见5.5.1节（禁用和/或限制使用的药物）；b)要求使用噻吩吡啶类药物[氯吡格雷或噻氯匹定，见5.5.2.1 阿司匹林 (ASA)和噻吩并吡啶类]。 7 其它排除标准:a)犯人或被强制性监禁（非自愿）的受试者；b)过去30天内曾使用一种研究药物或设备或既往曾随机分组到阿哌沙班临床研究中；c)被强制性监禁接受精神疾病或身体疾病（如传染病）治疗的患者 | ||
4、试验分组
| 试验药 | 序号 名称 用法 1 中文通用名:阿哌沙班(BMS-562247)包膜片5 mg 用法用量:片剂；规格5mg;口服，一天两次，每次5mg，用药时程：连续给药直至疾病进展或发生不可接受的毒性。 2 中文通用名:阿哌沙班(BMS-562247) 包膜片2.5 mg 用法用量:片剂；规格2.5mg;口服，一天两次，每次2.5mg，用药时程：连续给药直至疾病进展或发生不可接受的毒性。 |
|---|---|
| 对照药 | 序号 名称 用法 1 中文通用名:阿司匹林片剂81 mg 用法用量:片剂；规格81mg；每天1片、2片、3片或4片81mg的片剂（总量分别为81 mg, 162 mg, 243 mg 和 324 mg），口服，具体由研究者决定，用药时程：连续给药直至疾病进展或发生不可接受的毒性。 2 中文通用名:阿哌沙班(BMS-562247)包膜片的安慰剂2.5mg 用法用量:片剂；规格2.5mg；每次一片，一天2次；口服，用药时程：连续给药直至疾病进展或发生不可接受的毒性。 3 中文通用名:阿司匹林的安慰剂片 用法用量:片剂；规格81mg；每天1片、2片、3片或4片81mg的片剂（总量分别为81 mg, 162 mg, 243 mg 和 324 mg），口服，具体由研究者决定，用药时程：连续给药直至疾病进展或发生不可接受的毒性。 4 中文通用名:阿哌沙班(BMS-562247)包膜片的安慰剂5mg 用法用量:片剂；规格2.5mg；每次一片，一天2次；口服，用药时程：连续给药直至疾病进展或发生不可接受的毒性。 |
5、终点指标
| 主要终点指标及评价时间 | 序号 指标 评价时间 终点指标选择 1 至发生卒中或体循环栓塞复合终点的时间 本研究为事件驱动研究因而没有固定评价时间，评价从研究启动开始至有226名受试者发生了主要疗效事件时结束 有效性指标 2 至发生严重出血的时间 本研究为事件驱动研究因而没有固定评价时间，评价从研究启动开始至有226名受试者发生了主要疗效事件时结束 安全性指标 |
|---|---|
| 次要终点指标及评价时间 | 序号 指标 评价时间 终点指标选择 1 至发生卒中，体循环栓塞, 心肌梗死或血管性死亡 (重大血管性事件)的时间 本研究为事件驱动研究因而没有固定评价时间，评价从研究启动开始至有226名受试者发生了主要疗效事件时结束 有效性指标 2 至首次大出血或临床相关非大出血（CRNM）的时间。至双盲治疗期间的所有出血事件的时间。 本研究为事件驱动研究因而没有固定评价时间，评价从研究启动开始至有226名受试者发生了主要疗效事件时结束 安全性指标 |
6、数据安全监查委员会（DMC）
有
7、为受试者购买试验伤害保险
有
四、研究者信息
1、主要研究者信息
| 1 | 姓名 | 朱俊 | 学位 | 职称 | 教授 | |
|---|---|---|---|---|---|---|
| 电话 | 010-88398866 | junzhuld@hotmail.com | 邮政地址 | 北京市西城区北礼士路167号中国医学科学院阜外心血管病医院 | ||
| 邮编 | 100037 | 单位名称 | 中国医学科学院阜外心血管病医院 | |||
2、各参加机构信息
| 序号 | 机构名称 | 主要研究者 | 国家或地区 | 省（州） | 城市 |
|---|---|---|---|---|---|
| 1 | 中国医学科学院阜外心血管病医院 | 朱俊 | 中国 | 北京 | 北京 |
| 2 | 首都医科大学附属北京朝阳医院 | 杨新春 | 中国 | 北京 | 北京 |
| 3 | 上海交通大学医学院附属瑞金医院 | 陆国平 | 中国 | 上海 | 上海 |
| 4 | 上海长海医院 | 李莉 | 中国 | 上海 | 上海 |
| 5 | 哈尔滨医科大学第一医院 | 梁岩 | 中国 | 黑龙江 | 哈尔滨 |
| 6 | 武汉大学人民医院 | 蒋学俊 | 中国 | 湖北 | 武汉 |
| 7 | 中国医科大学第一附属医院 | 齐国先 | 中国 | 辽宁 | 沈阳 |
| 8 | 大连医大第一附院 | 高连君 | 中国 | 辽宁 | 大连 |
| 9 | 北京安贞医院 | 吴学思 | 中国 | 北京 | 北京 |
| 10 | 北京世纪坛医院 | 周北玲 | 中国 | 北京 | 北京 |
| 11 | 中国人民解放军第二炮兵总医院 | 胡桃红 | 中国 | 北京 | 北京 |
| 12 | 青岛市立医院 | 张放 | 中国 | 山东 | 青岛 |
| 13 | 广东省人民医院 | 吴书林 | 中国 | 广东 | 广州 |
| 14 | 中国人民解放军白求恩国际和平医院 | 李俊侠 | 中国 | 吉林 | 长春 |
| 15 | 中日友好医院 | 柯元南 | 中国 | 北京 | 北京 |
| 16 | 四川大学华西医院 | 陈晓平 | 中国 | 四川 | 成都 |
| 17 | 苏州大学附属第一医院 | 宋建平 | 中国 | 江苏 | 苏州 |
| 18 | 中国人民解放军总医院（301医院） | 杨庭树 | 中国 | 北京 | 北京 |
| 19 | Hospital Privado-Centro Medico De Cordoba S.A. | Amuchastegui, Luis Maria | Argentina | CORDOBA | Cordoba |
| 20 | Instituto Medico De La Comunidad (Imec) | Bustamante Labarta, Miguel Hugo | Argentina | BUENOS AIRES | Junin |
| 21 | Sanatorio Nuestra Senora Del Rosario | Bustamante, Gustavo | Argentina | JUJUY | San Salvador De Jujuy |
| 22 | Clinica Coronel Suarez | Caccavo, Alberto | Argentina | BUENOS AIRES | Coronel Suarez |
| 23 | Clinica Regional Del Este S.R.L. | Carmelo Paolasso, Horacio Cesar | Argentina | CORDOBA | San Francisco |
| 24 | Hospital Italiano De La Plata | Cartasegna, Luis Rodolfo | Argentina | BUENOS AIRES | La Plata |
| 25 | Clinica Privada Colombo | Colombo, Hugo Raul | Argentina | CORDOBA | Cordoba |
| 26 | Clinica Privada Del Prado | Covelli, Guillermo | Argentina | CORDOBA | Cordoba |
| 27 | Framingham Centro Medico | Cuadrado, Jesus Abel | Argentina | BUENOS AIRES | La Plata |
| 28 | Hospital Gen. De Agudos Jose Maria Ramos Mejia | Elizari, Marcelo Victor | Argentina | BUENOS AIRES | Buenos Aires |
| 29 | Clinica Privada Provincial S.A. | Garrido, Marcelo Alejandro | Argentina | BUENOS AIRES | Merlo |
| 30 | Instituto De Investigaciones Clinicas Quilmes | Hrabar, Adrian Demetrio | Argentina | BUENOS AIRES | Quilmes |
| 31 | Instituto De Investigaciones Clinicas De Mar Del Plata | Mackinnon, Ignacio Jorge | Argentina | BUENOS AIRES | Mar Del Plata |
| 32 | Centro Medico Consultan Salud | Marino, Javier Claudio | Argentina | BUENOS AIRES | Haedo |
| 33 | Dim Clinica Privada | Montana, Oscar Romano | Argentina | BUENOS AIRES | Ramos Mejia |
| 34 | Clinica Instituto Medico Adrogue | Schygiel, Pablo Omar | Argentina | BUENOS AIRES | Adrogue |
| 35 | Instituto De Investigaciones Clinicas Zarate | Vico, Marisa Liliana | Argentina | BUENOS AIRES | Zarate |
| 36 | Instituto De Investigaciones Clinicas Bahia Blanca | Vogel, Daniel Raul | Argentina | BUENOS AIRES | Bahia Blanca |
| 37 | Ciprec S.A. | Zaidman, Cesar Javier | Argentina | BUENOS AIRES | Autonoma |
| 38 | Clinica Chutro S.R.L. | Jure, Horacio Omar | Argentina | CORDOBA | Cordoba |
| 39 | Instituto Del Corazon | Kuschnir, Emilio | Argentina | CORDOBA | Cordoba |
| 40 | Clinica Privada Caraffa | Ramos, Hugo Roberto | Argentina | CORDOBA | Cordoba |
| 41 | Instituto De Cardiologia De Corrientes Juana Francisca Cabra | Pozzer, Domingo Luis | Argentina | CORRIENTES | Corrientes |
| 42 | Hospital San Bernardo | Cuneo, Carlos Alberto | Argentina | SALTA | Salta |
| 43 | Centro De Investigaciones Clinicas Del Litoral S.R.L. | Hominal, Miguel Angel | Argentina | SANTA FE | Santa Fe |
| 44 | Instituto De Investigaciones Clinicas De Rosario | Llanos, Javier | Argentina | SANTA FE | Rosario |
| 45 | Sanatorio Britanico De Rosario S.A. | Piskorz, Daniel Leonardo | Argentina | SANTA FE | Santa Fe |
| 46 | Hospital Italiano | Ramos, Jose Luis | Argentina | SANTA FE | Rosario |
| 47 | Investigaciones Clinicas Tucuman | Hasbani, Eduardo Gabriel | Argentina | TUCUMAN | San Miguel De Tucuman |
| 48 | Instituto De Cardiologia S.R.L. | Risso Patron, Facundo | Argentina | TUCUMAN | San Miguel De Tucuman |
| 49 | Concord Repatriation General Hospital | Brieger, David Bernard | Australia | New South Wales | Concord |
| 50 | Nepean Hospital | Coulshed, David | Australia | New South Wales | Penrith |
| 51 | Liverpool Hospital | French, John K | Australia | New South Wales | Sydney |
| 52 | Renal Research | Roger, Simon | Australia | New South Wales | Gosford |
| 53 | Northern Sydney Central Coast Area Health Service | Rogers, James | Australia | New South Wales | Gosford |
| 54 | St. George Private Hospital | Sader, Mark | Australia | New South Wales | Kogarah |
| 55 | Coffs Harbour Health Campus | Waites, Jonathon | Australia | New South Wales | Coffs Harbour |
| 56 | Core Research Group | Colquhoun, David | Australia | Queensland | Milton |
| 57 | Wesley Research Institute | Cross, David | Australia | Queensland | Auchenflower |
| 58 | Princess Alexandra Hospital | Garrahy, Paul | Australia | Queensland | Woolloongabba |
| 59 | Gold Coast Hospital | Jayasinghe, Rohan | Australia | Queensland | Southport |
| 60 | Peninsula Clin Rsrch Ctr | Karrasch, Jeffrey | Australia | Queensland | Kippa Ring |
| 61 | Peninsula Clinical Research Center | Karrasch, Jeffrey | Australia | Queensland | Kippa Ring |
| 62 | Geelong Hospital | Amerena, John | Australia | Victoria | Geelong |
| 63 | Joondalup Cardiovascular Trials Foundation Inc. | Purnell, Peter | Australia | Western Australia | Joondalup |
| 64 | Medizinische Universitat Graz | Fazekas, Franz | Austria | Graz | Graz |
| 65 | L K H-Univ. Klinikum Graz | Pieske, Burkert | Austria | Graz | Graz |
| 66 | Landes-Nervenklinik Wagner-Jauregg | Aichner, Franz | Austria | Linz | Linz |
| 67 | Krankenhaus Der Barmherzigen Brüder Linz | Eggers, Christian Claas | Austria | Linz | Linz |
| 68 | Allgemeines Krankenhaus Linz | Gruber, Franz | Austria | Linz | Linz |
| 69 | St. Johanns Spital-Salzburger Landeskliniken | Danmayr, Franz | Austria | Salzburg | Salzburg |
| 70 | A.O. Krankenhaus Oberpullendorf | Stockenhuber, Felix | Austria | Oberpullendorf | Oberpullendorf |
| 71 | Onze-Lieve-Vrouwziekenhuis | Jozef Goethals, Marc Antoon Maria | Belgium | Aalst | Aalst |
| 72 | Az Klina | Cools, Frank | Belgium | Brasschaat | Brasschaat |
| 73 | Universitair Ziekenhuis Brussel | Schoors, Danny | Belgium | Brussels | Brussels |
| 74 | Az Sint-Jan | Vandekerckhove, Yves | Belgium | Brugge | Brugge |
| 75 | Hopital Erasme | Jottrand, Maurice | Belgium | Bruxelles | Bruxelles |
| 76 | Cardio Vascular Detection Centre | Hollanders, Geert | Belgium | De Pinte | De Pinte |
| 77 | Heilig Hart Ziekenhuis Roeselare | Anne, Wim | Belgium | Roeselare | Roeselare |
| 78 | Az Turnhout Campus Sint-Elizabeth | J.F. Thoeng, John Khe Goan | Belgium | Turnhout | Turnhout |
| 79 | Chr De Huy | Marechal, Patrick | Belgium | Huy | Huy |
| 80 | Hartcentrum | Van Mieghem, Walter | Belgium | Genk | Genk |
| 81 | Fundacao Bahiana De Cardiologia | Rabelo Junior, Alvaro | Brazil | Bahia | Salvador |
| 82 | Real Sociedade Portguesa Beneficencia 16/Set - Hosp Prt | Teixeira, Marcelo | Brazil | Bahia | Salvador |
| 83 | Sociedade Educacional Uberabense | Avezum Oliveira, Livia Figueira | Brazil | Minas Gerais | Uberaba |
| 84 | Hospital Mater Dei Sa | Lichter, Artur Peretz | Brazil | Minas Gerais | Belo Horizonte |
| 85 | Santa Casa De Misericordia De Belo Horizonte | Reis, Gilmar | Brazil | Minas Gerais | Belo Horizonte |
| 86 | Universidade Federal Do Triangulo Mineiro | Salgado De Melo, Celso | Brazil | Minas Gerais | Uberaba |
| 87 | Associacao Beneficiente Bom Samaritano | D'Aurea Mora Jr., Raul | Brazil | Parana | Maringa |
| 88 | Nucleo De Pesquisa Clinica S/S | Ferreira Rossi, Paulo Roberto | Brazil | Parana | Curitiba |
| 89 | Irmandade Da Santa Casa De Misericordia De Curitiba | Moura Jorge, Jose Carlos | Brazil | Parana | Curitiba |
| 90 | Hospital De Clinicas Da Universidade Federal Do Parana | Pereira Da Cunha, Claudio Leinig | Brazil | Parana | Curitiba |
| 91 | Sociedade Hospitalar Angelina Caron | Precoma, Dalton Bertolim | Brazil | Parana | Campina Grande De Sul |
| 92 | Fundacao Publica Estadual Hosp. De Clin. Gaspar Vianna Fhcgv | Reis, Helder Jose Lima | Brazil | Para | Belem |
| 93 | Hospital Universitario Pedro Ernesto - Uerj | Albuquerque, Denilson Campos De | Brazil | Rio De Janeiro | Rio De Janeiro |
| 94 | Natal Hospital Center Sa | Paiva, Maria-Sanali | Brazil | Rio Grande Do Norte | Natal |
| 95 | Hospital Sao Lucas Da Pucrs | Abunader Kalil, Carlos Antonio | Brazil | Rio Grande do Sul | Porto Alegre |
| 96 | Fundacao Universitaria De Cardiologia | Dutra, Oscar Pereira | Brazil | Rio Grande do Sul | Porto Alegre |
| 97 | Fundacao Universitaria De Cardiologia | Glotz De Lima, Gustavo | Brazil | Rio Grande do Sul | Porto Alegre |
| 98 | Irmandade Da Santa Casa De Misericordia De Porto Alegre | Leaes, Paulo Ernesto | Brazil | Rio Grande do Sul | Porto Alegre |
| 99 | Associacao Educadora Sao Carlos Hospital Mae De Deus | Manenti, Euler R. Fernandes | Brazil | Rio Grande do Sul | Porto Alegre |
| 100 | Hospital Nossa Senhora Da Conceicao Sa | Pimentel Filho, Pedro | Brazil | Rio Grande do Sul | Porto Alegre |
| 101 | Hospital De Clinicas De Porto Alegre | Polanczyk, Carisi Anne | Brazil | Rio Grande do Sul | Porto Alegre |
| 102 | Secretaria De Estado De Saude Instituto De Cardiologia Ic | De Azeredo Coutinho, Mario Sergio Soares | Brazil | Santa Catarina | Sao Jose |
| 103 | Sociedade Divina Providencia Hospital Santa Isabel | Zimmermann, Sergio Luiz | Brazil | Santa Catarina | Blumenau |
| 104 | Hospital Estadual Mario Covas De Santo Andre | Aziz, Jose Luis | Brazil | Sao Paulo | Santo Andre |
| 105 | Braile Clinica De Servicos E Assistencia Medica Hospitalar | Braga Braile, Maria C.Valarie | Brazil | Sao Paulo | Sao Jose Do Rio Preto |
| 106 | Spdm / Hospital Sao Paolo | Carmargo Carvalho, Antonio Carlos De | Brazil | Sao Paulo | Sao Paulo |
| 107 | Instituto Dante Pazzanese De Cardiologia | De Figueredo, Oliveira B | Brazil | Sao Paulo | Sao Paulo |
| 108 | Unicardio Rio Preto Ltda. | Francischetti, Aloisio | Brazil | Sao Paulo | Sao Jose Do Rio Preto |
| 109 | Irmandade Da Santa Casa De Misericordia De Sao Paulo | Franken, Roberto Alexandre | Brazil | Sao Paulo | Sao Paulo |
| 110 | Prevencor, Centro De Prevencao E Tratamento Cardiovascular | Garbelini Junior, Benito | Brazil | Sao Paulo | Marilia |
| 111 | Instituto Do Coracao De Marilia | Guimaraes Filho, Fabio Villaca | Brazil | Sao Paulo | Marilia |
| 112 | Instituto Dante Pazzanese De Cardiologia | Indio Do Brasil, Clarisse Kaoru Ogawa | Brazil | Sao Paulo | Sao Paulo |
| 113 | Sociedade Campineira De Educacao E Instrucao | Kerr Saraiva, Jose Francisco | Brazil | Sao Paulo | Campinas |
| 114 | Instituto Dante Pazzanese De Cardiologia | Liporace, Idelzuita | Brazil | Sao Paulo | Sao Paulo |
| 115 | Equipamentos Cardiovasculares Rio Preto Ltda | Lorga Filho, Adalberto Menezes | Brazil | Sao Paulo | San Jose- Do Rio Preto |
| 116 | Faculdade Regional De Medicina Sao Jose Do Rio Preto | Maia, Lilia | Brazil | Sao Paulo | San Jose- Do Rio Preto |
| 117 | Instituto Dante Pazzanese De Cardiologia | Moreira, Dalmo Antonio R | Brazil | Sao Paulo | Sao Paulo |
| 118 | Faculdade De Medicina De Marilia | Pelloso, Eraldo Antonio | Brazil | Sao Paulo | Marilia |
| 119 | Incor-Hospital Das Clinicas Fmusp | Pereira Barretto, Antonio Carlos | Brazil | Sao Paulo | Sao Paulo |
| 120 | Universidade Estadual Paulista Julio De Mesquita Filho | Politi Okoshi, Marina | Brazil | Sao Paulo | Botucatu |
| 121 | Instituto De Ortopedia E Traumatologia (Iot) Do Hcfmusp | Sguizzatto, Guilherme Turolla | Brazil | Sao Paulo | Sao Paulo |
| 122 | Spdm / Hospital Sao Paolo | Vincenzo De Paola, Angelo Amato | Brazil | Sao Paulo | Sao Paulo |
| 123 | Dr. Patrick T S Ma | Ma, Patrick | Canada | Ab | Calgary |
| 124 | Dr. Akbarally V. Lalani | Lalani, Akbarally V | Canada | Bc | New Westminster |
| 125 | Rivergrove Medical Clinic | Saunders, Kevin K | Canada | Mb | Winnipeg |
| 126 | Randy Hart, Md | Hart, Randy | Canada | Nl | St. John's |
| 127 | Dr. Asaad Bakbak | Bakbak, Asaad I | Canada | On | Oshawa |
| 128 | Jbn Medical Diagnostic Services Inc | Berlingieri, Joseph C | Canada | On | Burlington |
| 129 | Heart Care Research | Bhargava, Rakesh | Canada | On | Oshawa, Ontario |
| 130 | St. Michael'S Hospital | Dorian, Paul | Canada | On | Toronto |
| 131 | Hamilton Health Sciences-Hamilton General Hospital Site | Eikelboom, John William Andrew | Canada | On | Hamilton |
| 132 | Dr. Martin Stephen Green | Green, Martin Stephen | Canada | On | Ottawa |
| 133 | Hamilton Health Sciences | Healey, Jeffrey Sean | Canada | On | Hamilton |
| 134 | Dr. Laurie Leigh Hill | Hill, Laurie Leigh | Canada | On | Brampton |
| 135 | Dr. Campbell Duncan Joyner | Joyner, Campbell Duncan | Canada | On | Toronto |
| 136 | Andy S.C. Lam West Lincoln Memorial Hospital | Lam, Andy | Canada | On | Grimsby |
| 137 | Shah Nawaz, Md | Nawaz, Shah | Canada | On | Sudbury |
| 138 | Michael F.J. O'Mahony London Road Dia Clin & Med Centre | O'Mahony, Michael F.J | Canada | On | Sarnia |
| 139 | Cambridge Cardiac Care Centre | Pandey, A. Shekhar | Canada | On | Cambridge |
| 140 | G.S. Cardiac Lab | Syan, Gurcharan Singh | Canada | On | Sudbury |
| 141 | Dr. Richard H. Tytus | Tytus, Richard | Canada | On | Hamilton |
| 142 | Dr. Saul Vizel Cardiac Research Office | Vizel, Saul | Canada | On | Cambridge |
| 143 | Louis C. H. Yao, Md | Yao, Louis C.H | Canada | On | Western |
| 144 | Pierre Jr. Boucher, Md | Boucher, Pierre Jr | Canada | Qc | Longueuil |
| 145 | Medicayeb Inc. | Chehayeb, Raja | Canada | Qc | Greenfield Park |
| 146 | Csss Du Sud De Lanaudiere-Hopital Pierre-Le Gardeur | Costi, Paolo | Canada | Qc | Terrebonne |
| 147 | Chum Hotel-Dieu | Coutu, Benoit | Canada | Qc | Montreal |
| 148 | Neufort Inc. | Fortin, Christian | Canada | Qc | St-lambert |
| 149 | Centre Hospitalier Regional De Lanaudiere | Kouz, Simon | Canada | Qc | St. Charles Borromee |
| 150 | Claude Maranda | Maranda, Claude | Canada | Qc | Westmount |
| 151 | St. Jerome Medical Research Inc. | Pesant, Yves | Canada | Qc | St. Jerome |
| 152 | Medi Recherche Inc. | Savard, Daniel | Canada | Qc | Montreal |
| 153 | Bureau Dr. Richard St. Hilaire | St. Hilaire, Richard | Canada | Qc | St. Georges Beauce |
| 154 | Mario Talajic, Md | Talajic, Mario | Canada | Qc | Montreal |
| 155 | Paul Talbot Jr., Md | Talbot Jr., Paul | Canada | Qc | Quebec |
| 156 | Dr. S. Bose Medical Professional Corporation | Bose, Sabyasachi | Canada | Sk | Saskatoon |
| 157 | Hospital De Victoria | Balboa Ormeno, Walter Ivan | Chile | ARAUCANIA | Victoria |
| 158 | Centro De Estudios Cardiológicos Y De Medicina Interna Ltda. | Lanas Zanetti, Fernando T | Chile | ARAUCANIA | Temuco |
| 159 | Sociedad De Prestaciones En Salud De Los Rios Ltda. | Garces, Eduardo | Chile | LOS RIOS | Valdivia |
| 160 | Clinica Alemana De Osorno | P-Cardenas, Sergio Hernan | Chile | LOS LAGOS | Osorno |
| 161 | Cardiocob Prestaciones Medicas | Cobos Segarra, Jorge Leonardo | Chile | METROPOLITANA | Santiago |
| 162 | Hospital Barros Luco Trudeau | Conejeros Kindel, Carlos Rafael | Chile | METROPOLITANA | Santiago |
| 163 | Hospital Clinico Pontificia Universidad Catolica De Chile | Corbalan Herreros, Ramon | Chile | METROPOLITANA | Santiago |
| 164 | Hospital Clinico San Borja Arriaran | Escobar Cerda, Edgardo | Chile | METROPOLITANA | Santiago |
| 165 | Hospital Dipreca | Varleta Olivares, Paola Elena | Chile | METROPOLITANA | Santiago |
| 166 | Centro De Estudios Clinicos | Raffo Grado, Carlos | Chile | VALPARAISO | Vina Del Mar |
| 167 | Clinica Medellin Sa | Botero Lopez, Rodrigo | Colombia | ANTIOQUIA | Medellin |
| 168 | Fundacion Cardioinfantil - Instituto De Cardiologia | Lopez Pareja, Monica | Colombia | Bogota | Bogota |
| 169 | Fundacion Valle Del Lili | Perafan Bautista, Pablo | Colombia | VALLE DEL CAUCA | Cali |
| 170 | Fundacion Cardiovascular De Colombia | Quiros Diaz, Franklin R | Colombia | SANTANDER | Floridablanca |
| 171 | Fundacion Del Caribe Para La Investigacion Biomedica | Triana, Miguel Alberto | Colombia | Barranquilla | Barranquilla |
| 172 | Fakultni Nemocnice U Svate Anny V Brne | Spac, Jiri | Czech Republic | Brno | Brno |
| 173 | Nemocnice Jindrichuv Hradec, A.S. | Ballek, Lubomir | Czech Republic | Jindrichuv Hradec | Jindrichuv Hradec |
| 174 | Dika Centrum, S.R.O. | Pederzoliova, Eva | Czech Republic | Havirov？mesto | Havirov？mesto |
| 175 | Oblastni Nemocnice Kladno A.S. | Stepanovova, Renata | Czech Republic | Kladno | Kladno |
| 176 | Kromerizska Nemocnice A.S. | Hejhal, Oldrich | Czech Republic | Kromeriz | Kromeriz |
| 177 | Interni Ordinace | Cisarova, Jana | Czech Republic | Praha | Praha |
| 178 | Orlickoustecka Nemocnice, A.S. | Dedek, Vratislav | Czech Republic | Usti Nad Orlici | Usti Nad Orlici |
| 179 | Vseobecna fakultni nemocnice v Praze | Gorican, Karel | Czech Republic | Praha 2 | Praha 2 |
| 180 | Preloucska Poliklinika A.S. | Hemzsky, Libor | Czech Republic | Prelouc | Prelouc |
| 181 | Mestska Nemocnice Mestec Kralove, a.s. | Hudcovic, Michal | Czech Republic | Mestec Kralove | Mestec Kralove |
| 182 | Med Point S.R.O. | Jansky, Petr | Czech Republic | Praha 5 | Praha 5 |
| 183 | Poliklinika Studentsky Dum | Kalousek, Igor | Czech Republic | Praha 6 | Praha 6 |
| 184 | Mestska Nemocnice Ostrava | Kovarova, Katerina | Czech Republic | Ostrava | Ostrava |
| 185 | Nemocnice Slany | Marcinek, Gabriel | Czech Republic | Slany | Slany |
| 186 | Oblastni Nemocnice Pribram, A.S. | Polak, Martin | Czech Republic | Pribram | Pribram |
| 187 | Interni A Diabetologica Ambulance | Stipal, Roman | Czech Republic | Ostrava | Ostrava |
| 188 | Kardiologicka Ambulance | Velimsky, Tomas | Czech Republic | Pisek | Pisek |
| 189 | Regionshospitalet Randers | Bertelsen, Jette | Denmark | Randers | Randers |
| 190 | Sydvestjysk Sygehus Esbjerg | Friis, Elsebeth Vibeke | Denmark | Esbjerg | Esbjerg |
| 191 | Arhus Sygehus | Husted, Steen | Denmark | Arhus C | Arhus C |
| 192 | Odense Universitets Hospital | Pedersen, Knud Erik | Denmark | Odense | Odense |
| 193 | Frederiksberg Hospital | Urhammer, Soren | Denmark | Frederiksberg | Frederiksberg |
| 194 | Huch Jorvi Hospital | Manttari, Matti | Finland | Espoo | Espoo |
| 195 | Suomen Terveystalo | Melin, John | Finland | Jyvaskyla | Jyvaskyla |
| 196 | Hatanpaan Sairaala, Osasto B5 | Nikkila, Matti | Finland | Tampere | Tampere |
| 197 | Mehilainen Oy | Peuhkurinen, Keijo | Finland | Kuopio | Kuopio |
| 198 | Helsinki University Central Hospital | Toivonen, Lauri | Finland | Helsinki | Helsinki |
| 199 | Chu De Grenoble, Hopital Nord - Albert Michallon | Defaye, Pascal | France | Grenoble Cedex 09 | Grenoble Cedex 09 |
| 200 | Centre Hospitalier De Cholet | Gacem, Karim | France | Cholet | Cholet |
| 201 | Centre Hospitalier General D'Albi | Galley, Daniel | France | Albi Cedex 9 | Albi Cedex 9 |
| 202 | Centre Hospitalier De Langres | Martelet, Michel | France | Langres | Langres |
| 203 | Centre Hospitalier D'Abbeville | Poulard, Jean-Ernst | France | Abbeville | Abbeville |
| 204 | Hopital Bichat Claude Bernard | Amarenco, Pierre | France | Paris | Paris |
| 205 | Hopital Bichat Claude Bernard | Steg, Philippe Gabriel | France | Paris | Paris |
| 206 | Hia Sainte Anne | Laurent, Pierre | France | Toulon Armees | Toulon Armees |
| 207 | Centre Hospitalier Intercommunal Des Alpes Du Sud | Olive, Thierry | France | Sisteron | Sisteron |
| 208 | Kreiskrankenhaus Altenburg | Berrouschot, J？rg | Germany | Altenburg | Altenburg |
| 209 | Charite Campus Virchow Klinikum | Haverkamp, Wilhelm | Germany | Berlin | Berlin |
| 210 | Vivantes Wenckebach-Kliniken | Henzgen, Rudolf | Germany | Berlin | Berlin |
| 211 | Helios Klinikum Berlin-Buch | Monti, Jan | Germany | Bonn | Bonn |
| 212 | St. Marien Hospital | Omran, Heyder | Germany | Berlin | Berlin |
| 213 | Vivantes Auguste-Viktoria Klinikum | Schuhlen, Helmut | Germany | Berlin | Berlin |
| 214 | Praxis Fur Kardiologische Diagnostik | Schulze, Uwe | Germany | Berlin | Berlin |
| 215 | Universitaetsmedizin Berlin - Charité-Campus Mitte | Stangl, Verena | Germany | Berlin | Berlin |
| 216 | Klinikum Der Johann Wolfgang Goethe-Universitat | Hohnloser, Stefan | Germany | Frankfurt am Main | Frankfurt am Main |
| 217 | Institut Für Klinische Forschung | Sehnert, Walter | Germany | Dortmund | Dortmund |
| 218 | Universit？tsklinikum Essen | Weimar, Christian | Germany | Essen | Essen |
| 219 | Universit？tsklinik Und Poliklinik Für Innere Medizin Iii | Ebelt, Henning | Germany | Halle/saale | Halle/saale |
| 220 | Asklepios Klinik Barmbek | Groenefeld, Gerian | Germany | Hamburg | Hamburg |
| 221 | Universitares Herz- Und Gafasszentrum | Mathey, Detlef | Germany | Hamburg | Hamburg |
| 222 | Praxis Dr. Sperling | Sperling, Karsten | Germany | Hamburg | Hamburg |
| 223 | Ambulantes Herzzentrum Kassel | Appel, Karl-Friedrich | Germany | Kassel | Kassel |
| 224 | Kliniken Der Stadt Koln Ggmgh | Dormann, Arno | Germany | Koln | Koln |
| 225 | Medizinische Universitatsklinik Heidelberg (Krehl-Klinik) | Licka, Manuela | Germany | Heidelberg | Heidelberg |
| 226 | Heidelberger Praxisklinik Fur Kardiologie | Natour, Mohammed | Germany | Heidelberg | Heidelberg |
| 227 | Asklepios Kliniken Langen | Olbrich, Hans-Georg | Germany | Langen | Langen |
| 228 | Gemeinschaftspraxis Dres. Lobe, Weissbrodt, Boran | Weissbrodt, Matthias | Germany | Leipzig | Leipzig |
| 229 | Kardiologische Praxis Mainz | Drexler, Michael | Germany | Mainz | Mainz |
| 230 | Universitaetsklinikum Mannheim | Harenberg, Job | Germany | MANNHEIM | MANNHEIM |
| 231 | Klinikum Mannheim- Universitatsklinikum | Hoffmann, Ursula | Germany | MANNHEIM | MANNHEIM |
| 232 | Klinikum Der Johannes Gutenberg Universitaet Mainz | Munzel, Thomas | Germany | Mainz | Mainz |
| 233 | Marienkrankenhaus Papenburg Gmbh | Pollock, Berthold | Germany | Papenburg | Papenburg |
| 234 | Kardiologische Gemeinschaftpraxis Riesa | Ebert, Hans-Holger | Germany | Riesa | Riesa |
| 235 | Marienkrankenhaus Ggmbh | Flesch, Markus | Germany | Soest | Soest |
| 236 | Evangelisches Krankenhaus Witten | Horacek, Thomas | Germany | Witten | Witten |
| 237 | Forschungszentrum Ruhr | Kahrmann, Gerd | Germany | Witten | Witten |
| 238 | Universitat Regensburg, Berzirksklinikum Regensburg | Rochus Schlachetzki, Felix J | Germany | Regensburg | Regensburg |
| 239 | Institut Fuer Klinische Forschung | Schumacher, Michael | Germany | Wolmirstedt | Wolmirstedt |
| 240 | General Hospital Of Athens-Hippocratio | Kallikazaros, Ioannis | Greece | Athens | Athens |
| 241 | General Hospital Of Larissa | Karamitsos, Konstantinos | Greece | Larisa | Larisa |
| 242 | Diagnostic And Therapeutic Center Of Athens-Hygeia | Karatzas, Nicholas | Greece | Athens | Athens |
| 243 | General Hospital Of Thiva | Skoumpourdis, Emmanouil | Greece | Thiva | Thiva |
| 244 | Pamela Youde Nethersole Eastern Hospital | Li, Shu Kin | China | HONGKONG | HONGKONG |
| 245 | Prince Of Wales Hospital | Sing Wong, Lawrence Ka | China | HONGKONG | HONGKONG |
| 246 | Queen Mary Hospital | Tse, Hung Fat | China | HONGKONG | HONGKONG |
| 247 | Mgm Medical College & My Hospital | Bharani, Anil | India | Indore | Indore |
| 248 | St. John'S Medical College Hospital | Iyengar, Shamanna | India | Bangalore, Karnataka | Bangalore, Karnataka |
| 249 | Caritas Hospital | Joseph, Johny | India | Kottayam | Kottayam |
| 250 | Cresent Hospital And Heart Centre | Khan, Aziz | India | Dhantoli | Dhantoli |
| 251 | Care Institute Of Medical Sciences | Naik, Ajay M | India | Ahmedabad | Ahmedabad |
| 252 | S.P. Medical College And A.G. Hospitals | Panwar, Raja Babu | India | Bikaner | Bikaner |
| 253 | Medwin Hospitals | Ramesh Babu, Byrapaneni | India | Andhra Pradesh | Hyderabad |
| 254 | Bhagawan Mahaveer Jain Heart Centre | Ramesh, Srinivasaiah | India | Karnataka | Bangalore |
| 255 | Vikram Hospital & Heart Care | Srinivas, Arun | India | Mysore | Mysore |
| 256 | Shree Sai Baba Heart Hospital And Research Center | Dharmadhikari, Aniruddha | India | Maharashtra | Nashik |
| 257 | Gautams Clinic | Gautam, Nilesh | India | Maharashtra | Mumbai |
| 258 | Poona Hospital And Research Centre | Hiremath, Jagdish | India | Maharashtra | Pune |
| 259 | Avanti Institute Of Cardiology Pvt. Ltd | Jain, Archana Santosh | India | Maharashtra | Nagpur |
| 260 | Pulse Diagnostix Cardiac & Medical Centre | Srikanthan, Vinjamur | India | Maharashtra | Pune |
| 261 | Bhatia Hospital | Thacker, Hemant | India | Maharashtra | Mumbai |
| 262 | S R Kalla Memorial Gastro & General Hospital | Gupta, Jugal Bihari | India | Rajasthan | Jaipur |
| 263 | M V Hospital And Research Centre | Gupta, Sandeep Kumar | India | Uttar Pradesh | Lucknow |
| 264 | Apollo Hospitals | Oomman, Abraham | India | Tamil Nadu | Chennai |
| 265 | Dr Soetomo General Hospital | Baktijasa Dharmadjati, Budi | Indonesia | Surabaya | Surabaya |
| 266 | Syaiful Anwar Hospital | Hendrawan, Dadang | Indonesia | Malang | Malang |
| 267 | Sanglah Hospital | Nadha, Ketut Badjra | Indonesia | Denpasar | Denpasar |
| 268 | Dr M. Djamil Hospital | Syafri, Masrul | Indonesia | Padang | Padang |
| 269 | Dr M. Hoesin Hospital | Syawal, Aulia | Indonesia | Palembang | Palembang |
| 270 | Rsup. Dr. Hasan Sadikin | Yahya, Achmad Fauzi | Indonesia | Bandung | Bandung |
| 271 | Binawaluya Hospital | Munawar, Muhammad | Indonesia | Jakarta Timur | Jakarta Timur |
| 272 | Sardjito General Hospital | Setianto, Budi Yuli | Indonesia | Yogyakarta | Yogyakarta |
| 273 | Premier Jatinegara Hospital | Tedjasukmana, Pradana | Indonesia | Jakarta | Jakarta |
| 274 | Cipto Mangunkusumo Hospital | Yamin, Muhammad | Indonesia | Jakarta | Jakarta |
| 275 | Rambam Medical Center | Brenner, Benjamin | Israel | Haifa | Haifa |
| 276 | Barzilai Hospital | Katz, Amos | Israel | Ashkelon | Ashkelon |
| 277 | Gefen Cardiac Health Center | Klainman, Eliezer | Israel | Givatayim | Givatayim |
| 278 | Lady Davis Carmel Medical Center | Lewis, Basil | Israel | Haifa | Haifa |
| 279 | Hillel Yaffe Medical Center | Shocht, Michael | Israel | Hadera | Hadera |
| 280 | Ha'Emek Medical Center | Turgeman, Yoav | Israel | Afula | Afula |
| 281 | Holy Family Hospital | Francis, Adi | Israel | Nazareth | Nazareth |
| 282 | Rabin Mc | Lahav, Meir | Israel | Petach-tikva | Petach-tikva |
| 283 | Sieff Medical Center | Marmor, Alon | Israel | Safed | Safed |
| 284 | Nazareth Hospital Emms | Omary, Muhamad | Israel | Nazareth | Nazareth |
| 285 | Tel Aviv Sourasky Medical Center | Viskin, Samuel | Israel | Tel Aviv | Tel Aviv |
| 286 | The Edith Wolfson Medical Center | Zimlichman, Reuven | Israel | Holon | Holon |
| 287 | Azienda Ospedaliera Universitaria S. Martino | Balbi, Manrico | Italy | Genova | Genova |
| 288 | Ospedale | Casolo, Giancarlo | Italy | Lido Di Camaiore | Lido Di Camaiore |
| 289 | Univ. Studi | De Caterina, Raffaele | Italy | Chieti | Chieti |
| 290 | Ospedale Mazzoni | Moretti, Luciano | Italy | Ascoli Piceno | Ascoli Piceno |
| 291 | Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone | Novo, Salvatore | Italy | Palermo | Palermo |
| 292 | Ospedale F. Veneziale Centro Per L'Ipertensione Arteriosa | Olivieri, Carlo | Italy | Isernia | Isernia |
| 293 | Universita E Azienda Ospedaliera Di Perugia | Bentivoglio, Maurizio | Italy | Perugia | Perugia |
| 294 | Azienda Ospedaliero Universitaria | Glorioso, Nicola | Italy | Sassari | Sassari |
| 295 | Ospedale Unico Di Rete Sant'Antonio | Mos, Lucio | Italy | San Daniele Del Fruli | San Daniele Del Fruli |
| 296 | Presido Ospedaliero Di Sassari- Ospedale Ss Annunziata | Terrosu, Pierfranco | Italy | Sassari | Sassari |
| 297 | Kon Yang University Hospital | Bae, Jangho | Republic of korea | Daejeon | Daejeon |
| 298 | Kosin University Gospel Hospital | Cha, Tae-Joon | Republic of korea | Busan | Busan |
| 299 | Kyungpook National University Hospital | Chae, Shung Chull | Republic of korea | Daegu | Daegu |
| 300 | Dongguk University International Hospital | Lee, Myoung Mook | Republic of korea | GYEONGGI-DO | Goyang-si |
| 301 | Chonnam National University Hospital | Cho, Jeong Gwan | Republic of korea | Gwangju | Gwangju |
| 302 | Seoul National University Bundang Hospital | Kim, Cheol Ho | Republic of korea | Seongnam-si | Seongnam-si |
| 303 | Hanyang University, Kuri Hospital | Kim, Soon Kil | Republic of korea | KYUNGGI-DO | Kuri-city |
| 304 | Konkuk University Hospital | Kim, Hyun-Joong | Republic of korea | Seoul | Seoul |
| 305 | The Catholic University Of Korea St. Paul'S Hospital | Kim, Jae Hyung | Republic of korea | Seoul | Seoul |
| 306 | Seoul National University Hospital | Oh, Seil | Republic of korea | Seoul | Seoul |
| 307 | University Malaya Medical Centre | Chee, Kok Han | Malaysia | KUALA LUMPUR | Kuala Lumpur |
| 308 | Hospital Sultanah Aminah | Lee, Chuey Yan | Malaysia | JOHOR | Johor Bahru |
| 309 | Universiti Kebangsaan Malaysia Medical Centre | Maskon, Oteh | Malaysia | KUALA LUMPUR | Cheras |
| 310 | Hospital Kuala Lumpur | Sinnadurai, Jeyaindran | Malaysia | KUALA LUMPUR | Kuala Lumpur |
| 311 | Hospital Pulau Pinang | Ismail, Omar | Malaysia | PENANG | Pulau Pinang |
| 312 | Sarawak General Hospital | Kui-Hian, Sim | Malaysia | SARAWAK | Kuching |
| 313 | Unidad De Investigacion En Salud De Chihuahua Sc | Acosta Grajeda, Jesus Manuel | Mexico | Chihuahua | Chihuahua |
| 314 | Fundacion Cardiovascular De Aguascalientes A.C. | Bayram Llamas, Edmundo | Mexico | Aguascalientes | Aguascalientes |
| 315 | Hospital Angeles Del Pedregal | Escarcega, Joseluis | Mexico | Distrito Federal | Mexico City |
| 316 | Hospital General De Mexico | Fernandez, Luis | Mexico | Distrito Federal | Mexico City |
| 317 | Instituto Nacional De Cardiologia Dr. Ignacio Chavez | Gonzalez-Hermosillo, J. Antonio | Mexico | Distrito Federal | Mexico |
| 318 | Instituto Biomedico De Investigacion A.C | Ramirez Isunza, Jose Manuel | Mexico | Aguascalientes | Aguascalientes |
| 319 | Cardioprevent Clinica De Prevencion Cardiovascul. Y Diabetes | Alvarado Ruiz, Ricardo | Mexico | Durango | Durango |
| 320 | Hosp. Gen. De Atizapan Dr. S. G. Herrejon, Daimler-Chrysler | Calderon Marquez, Maria Antonieta J | Mexico | Estado De Mexico | Atizapan De Zaragoza |
| 321 | Hospital General De Acapulco | Matadamas, Norberto | Mexico | Guerrero | Acapulco |
| 322 | Clinica De Estudios Medicos S.C. | Olvera, Rafael | Mexico | Jalisco | Guadalajara |
| 323 | Francisco Javier Robles Torres, Md - Private Practice | Robles Torres, Francisco Javier | Mexico | Jalisco | Guadalajara |
| 324 | Hospital Dr. Angel Leano | Velasco Sanchez, Raul Gerardo | Mexico | Jalisco | Zapopan |
| 325 | Instituto De Corazon De Queretaro | Alcocer, Marco | Mexico | Queretaro | Queretaro |
| 326 | Hospital Angeles Centro Medico Del Potosi | Arenas Leon, Jose Luis | Mexico | San Luis Potosi | San Luis Potosi |
| 327 | Hospital Central | Leiva Pons, Jose Luis | Mexico | San Luis Potosi | San Luis Potosi |
| 328 | Unidad Medica De Tratamientos Avanzados, Sc | Lopez Villezca, David | Mexico | Nuevo Leon | Monterrey |
| 329 | Cardioarritmias E Investigacion S.C. | Rodriguez Briones, Ignacio | Mexico | San Luis Potosi | San Luis Potosi |
| 330 | Hospital Angeles Culiacan | De Los Rios Ibarra, Manuel Odin | Mexico | Sinaloa | Culiacan |
| 331 | Centro De Espec. Medicas Del Est. De Veracruz 'Dr. R. Lucio' | Lopez Rosas, Enrique | Mexico | Veracruz | Xalapa |
| 332 | Hospital Centro Medico | Ruiz Gastelum, Edith Dalila | Mexico | Sonora | Hermosillo |
| 333 | Oslo Universitetssykehus Hf Ulleval | Berge, Eivind | Norway | Oslo | Oslo |
| 334 | Dr. Erik Buchmann | Buchmann, Erik | Norway | Oslo | Oslo |
| 335 | Kristiansund Sykehus, Helse Nordm？re Og Romsdal | Dimmen, Arild | Norway | Kristiansund | Kristiansund |
| 336 | Vestre Viken Hf, Kongsberg Sykehus | Meen, Oystein | Norway | Kongsberg | Kongsberg |
| 337 | Hospitalet Betanien | Nakling, Arne E | Norway | Fyllingsdal | Fyllingsdal |
| 338 | Perpetual Help University | Brillantes, Amelita | Philippines | Binan | Binan |
| 339 | Philippine General Hospital | Dans, Antonio Miguel | Philippines | Manila | Manila |
| 340 | Cagayan De Oro Medical Center | Edmilao, Manuel Ignatius | Philippines | MISAMIS ORIENTAL | Cagayan De Oro City |
| 341 | Private Clinic Of Dr. Ellen Morales-Palomares | Morales-Palomares, Ellen | Philippines | ILOCOS NORTE | Laoag City |
| 342 | De La Salle University Medical Center | Rey, Nannette | Philippines | Cavite | Cavite |
| 343 | University Of Perpetual Help Dalta Medical Center | Sevilla, Maria Rosario | Philippines | Las Pinas City | Las Pinas City |
| 344 | Mindanao Sanitarium And Hospital | Timonera, Miriam | Philippines | LANAO DEL NORTE | Iligan City |
| 345 | Dr. Pablo O. Torre Memorial Hospital | Villacin, Luciene | Philippines | NEGROS OCCIDENTAL | Bacolod City |
| 346 | Niepubliczny Zaklad Opieki Zdrowotnej Esculap | Derezinski, Tadeusz | Poland | Gniewkowo | Gniewkowo |
| 347 | Spzoz Miejski Szpital Zespolony | Janik, Krzysztof | Poland | Czestochowa | Czestochowa |
| 348 | Nzoz Vito-Med Sp. Z O.O. | Krauze-Wielicka, Magdalena | Poland | Gliwice | Gliwice |
| 349 | Nzoz Pro Cordis Sopockie | Miekus, Pawel | Poland | Gdynia | Gdynia |
| 350 | Wojewodzki Szpital Zespolony W Elblagu | Reszka, Zygfryd | Poland | Elblag | Elblag |
| 351 | Spzoz Szpital Zachodni Im. Jana Pawla Ii | Stopinski, Marek | Poland | Grodzisk Mazowiecki | Grodzisk Mazowiecki |
| 352 | Publiczny Specjalistyczny Zaklad Opieki Zdrowotnej | Bronisz, Marek Aleksander | Poland | Inowroclaw | Inowroclaw |
| 353 | Spzoz Lubartow | Gieroba, Andrzej | Poland | Lubartow | Lubartow |
| 354 | Swietokrzyskie Centrum Kardiologii | Janion, Marianna | Poland | Kielce | Kielce |
| 355 | Przychodnia Lekarsko-Stomatologiczna Dentmal | Malinowski, Stanislaw | Poland | Nowy Sacz | Nowy Sacz |
| 356 | Prywatny Gabinet Lekarski Michal Ogorek | Ogorek, Michal | Poland | Piotrkow Trybunalski | Piotrkow Trybunalski |
| 357 | Nzoz | Peruga, Jan | Poland | Lodz | Lodz |
| 358 | Nzoz Solumed | Boruczkowska-Kaszkowiak, Anna | Poland | Poznan | Poznan |
| 359 | Wielospecjalistyczny Niepubliczny Zaklad Opieki Zdrowotnej | Kincel, Krzysztof | Poland | Siemianowice Slaskie | Siemianowice Slaskie |
| 360 | Specjalistyczna Przychodnia Lekarska | Korzeniak, Romuald | Poland | Plock | Plock |
| 361 | Sp Zoz Pulawy | Monies, Franciszek | Poland | Pulawy | Pulawy |
| 362 | Spzoz Szpital Wegrow, Oddzial Internistyczno-Kardiologiczny | Czerski, Tomasz | Poland | Wegrow | Wegrow |
| 363 | Specjalistyczny Gabinet Lekarski | Derlaga, Boguslaw | Poland | Tarnow | Tarnow |
| 364 | Nzoz Przychodnia | Kania, Grzegorz | Poland | Skierniewice | Skierniewice |
| 365 | Wojewodzki Szpital Zespolony | Kawka-Urbanek, Teresa | Poland | Skierniewice | Skierniewice |
| 366 | Nzoz Starowka | Zarebinski, Maciej | Poland | Warsaw | Warsaw |
| 367 | Spzoz Szpital Grochowski Im Dr R. Masztaka | Budaj, Andrzej | Poland | Warszawa | Warszawa |
| 368 | Wojewodzki Szpital Brodnowski, Sp Zoz | Dluzniewski, Miroslaw | Poland | Warszawa | Warszawa |
| 369 | Slaskie Centrum Chorob Serca | Kalarus, Zbigniew | Poland | Zabrze | Zabrze |
| 370 | Szpitala Uniwersyteckiego W Krakowie | Kawecka-Jaszcz, Kalina | Poland | Krakow | Krakow |
| 371 | Amicor Centrum Kardiologiczne | Piotrowski, Wieslaw | Poland | Krakow | Krakow |
| 372 | Gabinet Lekarski Dr. Med. Ryszard Serafin-Kardiolog | Serafin, Ryszard | Poland | Zarow | Zarow |
| 373 | Regional St. Healthcare Inst. Altai Reg. Cardiol. Dispensary | Duda, Alexey | Russian Federation | Barnaul | Barnaul |
| 374 | Medical Association, Novaya Bolnitsa | Fokina, Elena | Russian Federation | Ekaterinburg | Ekaterinburg |
| 375 | Ural Institute Of Cardiology | Freydlin, Marina | Russian Federation | Ekaterinburg | Ekaterinburg |
| 376 | City Clinical Hospital #3 | Levin, Alexander | Russian Federation | Chelyabinsk | Chelyabinsk |
| 377 | Kaluga Regional Hospital | Pasechnik, Elena | Russian Federation | Kaluga | Kaluga |
| 378 | Municipal Inst Healthcare | Barbarash, Olga | Russian Federation | Kemerovo | Kemerovo |
| 379 | Kazan State Medical Univ. | Kamalov, Gadel | Russian Federation | Kazan | Kazan |
| 380 | Kuban St Med Univ,Dept Hosp Therapy Based Emer Med Care Hosp | Kanorsky, Sergey | Russian Federation | Krasnodar | Krasnodar |
| 381 | State Education Institution Of Higher Professional Education | Shvarts, Yury | Russian Federation | Kazan | Kazan |
| 382 | Municipal Medical And Prophylactic Instit. City Hospital #28 | Suvorov, Alexander | Russian Federation | Nizhniy Novgorod | Nizhniy Novgorod |
| 383 | Muz Budget Novosibirsk City Clinical Hospital #1 | Barbarich, Vladimir | Russian Federation | Novosibirsk | Novosibirsk |
| 384 | Sei Kpe Perm State Medical Academy Of Roszdrav | Koziolova, Natalya | Russian Federation | Perm | Perm |
| 385 | Municipal Health Care Institution/City Clinical Hospital #4 | Lapin, Oleg | Russian Federation | Perm | Perm |
| 386 | Novosibirsk Regional Clinical Cardiological Dispensary | Yakhontova, Polina | Russian Federation | Novosibirsk | Novosibirsk |
| 387 | State Inst. For Healthcare, Leningrad Regional Clinic. Hosp. | Butynskaya, Emilia | Russian Federation | Saint-petersburg | Saint-petersburg |
| 388 | Saint Petersburg State Institution of Healthcare War Veterans Hospital | Konstantinov, Vladimir | Russian Federation | Saint-petersburg | Saint-petersburg |
| 389 | Spb National Healthcare Instit. City Outpatient Clinic No 34 | Nosova, Nina | Russian Federation | Saint-petersburg | Saint-petersburg |
| 390 | Medem International Clinic And Hospital | Obrezan, Andrey | Russian Federation | Saint-petersburg | Saint-petersburg |
| 391 | Saint-Petersburg Krasnogvardeysky Dist Med Sports Dispensary | Sherenkov, Alexander O | Russian Federation | Saint-petersburg | Saint-petersburg |
| 392 | Federal Center Of Heart, Blood, Endocrinology | Tatarsky, Boris | Russian Federation | Saint-petersburg | Saint-petersburg |
| 393 | Fed Ctr Of Heart,Blood & Endocrinology Named Aft V.A.Almazov | Treshkur, Tatiana | Russian Federation | Saint-petersburg | Saint-petersburg |
| 394 | Saint-Petersburg Municipal Hospital #28 | Zalevsky, Grigory | Russian Federation | Saint-petersburg | Saint-petersburg |
| 395 | Clinical City Hospital #46 | Zotov, Dmitriy | Russian Federation | Saint-petersburg | Saint-petersburg |
| 396 | Federal St Budget Inst. Out-Patient Clinic #5 Of Russian Fed | Aleksandrova, Elena | Russian Federation | Moscow | Moscow |
| 397 | Municipal Clinical Hospital #23 Named After Medsantrud | Arkhipov, Vladimir | Russian Federation | Moscow | Moscow |
| 398 | Russian St Med Univ, Dept Of Outpat. Therapy Diag Clin Ctr 1 | Bart, Boris | Russian Federation | Moscow | Moscow |
| 399 | Russian State Medical University | Belousov, Yuri | Russian Federation | Moscow | Moscow |
| 400 | State Research Center For Preventive Medicine | Bochkareva, Elena | Russian Federation | Moscow | Moscow |
| 401 | Federal State Healthcare Inst Clin Hosp123 Of Fmba Of Russia | Chernichka, Irina | Russian Federation | Moscow | Moscow |
| 402 | Russian Fed Def. Ministry Burdenko Main Military Clin. Hosp. | Chernov, Sergey | Russian Federation | Moscow | Moscow |
| 403 | Fed St Inst Rus Card Res&Prod Ctr, Min Of Hlth&Sd Of Rus Fed | Golitsyn, Sergey | Russian Federation | Moscow | Moscow |
| 404 | Fgu Cent. Clin Hosp Of Civ Aviat Of Min Of Transp Of Rus Fed | Gorbachenkov, Anatoly | Russian Federation | Moscow | Moscow |
| 405 | O.M. Filatov City Clinical Hospital #15 | Gordeev, Ivan | Russian Federation | Moscow | Moscow |
| 406 | City Clinical Hospital Named After S.P. Botkin | Libov, Igor | Russian Federation | Moscow | Moscow |
| 407 | Moscow State Univ. Of Medicine And Dentistry Clin Hosp #40 | Martynov, Anatoly | Russian Federation | Moscow | Moscow |
| 408 | Veterans Hospital No. 3, Cardiology Department | Mkrtchian, Vagan | Russian Federation | Moscow | Moscow |
| 409 | Fed St Inst Rus Card Res&Prod Ctr, Min Of Hlth&Sd Of Rus Fed | Panchenko, Elizaveta | Russian Federation | Moscow | Moscow |
| 410 | Russian State Medical University | Poteshkina, Nataliya | Russian Federation | Moscow | Moscow |
| 411 | Fgu Central Clinical Hospital With Polyclinic Of President | Vaniev, Sergey | Russian Federation | Moscow | Moscow |
| 412 | State Institution Of Healthcare Samara Reg Cardio Dispensary | Duplyakov, Dmitry | Russian Federation | Samara | Samara |
| 413 | Yaroslavl Regional Clinical Hospital | Khrustalev, Oleg | Russian Federation | Yaroslavl | Yaroslavl |
| 414 | Samara Regional Clinical Hospital Named After M.I. Kalinin | Lebedev, Petr | Russian Federation | Samara | Samara |
| 415 | Tver Regional Clinical Hospital | Mazur, Evgeniy | Russian Federation | Tver | Tver |
| 416 | Research Institute Of Cardiology | Popov, Sergey | Russian Federation | Tomsk | Tomsk |
| 417 | Saratov Scientific Research Institute Of Cardiology | Reshetko, Olga | Russian Federation | Saratov | Saratov |
| 418 | State Autonomy Institute of Health of Tyumen Region | Shalaev, Sergey | Russian Federation | Tumen | Tumen |
| 419 | State Healthcare Inst., Ryazan Reg. Cardiological Dispensary | Yakushin, Sergey | Russian Federation | Ryazan | Ryazan |
| 420 | Tan Tock Seng Hospital | Foo, David | Singapore | Singapore | Singapore |
| 421 | Khoo Teck Puat Hospital | Ong, Hean Yee | Singapore | Singapore | Singapore |
| 422 | National Heart Centre Of Singapore | Tan, Ru San | Singapore | Singapore | Singapore |
| 423 | Changi General Hospital | Tong, Khim Leng | Singapore | Singapore | Singapore |
| 424 | Rosepark Hospital | Bester, Frederik | South Africa | FREE STATE | Bloemfontein |
| 425 | Netcare Private Hospital | Theron, Hennie Du Toit | South Africa | FREE STATE | Bloemfontein |
| 426 | Wilgers Medical Consortium | Snyders, F. A | South Africa | GAUTENG | Pretoria |
| 427 | Emmed Research Cc | Van Nieuwenhuizen, Elane | South Africa | GAUTENG | Pretoria |
| 428 | Union Hospital | Venter, Tjaart Petrus | South Africa | GAUTENG | Alberton |
| 429 | Groote Schuur Hospital | Commerford, Patrick Joseph | South Africa | WESTERN CAPE | Cape Town |
| 430 | Vergelegen Medi Clinic | Engelbrecht, Johannes Mattheus | South Africa | WESTERN CAPE | Somerset West |
| 431 | Tiervlei Trial Center | Pretorius, Maria M | South Africa | WESTERN CAPE | Bellville, Cape Town |
| 432 | Clinical Projects Research Sa (Pty) Ltd | Van Zyl, Louis J | South Africa | WESTERN CAPE | Worcester |
| 433 | Hospital Universitario Nuestra Senora Del Perpetuo Socorro | Abizanda Soler, Pedro | Spain | Albacete | Albacete |
| 434 | Hospital Universitario San Cecilio | Correa, Concepcion | Spain | Granada | Granada |
| 435 | Consorcio Hospital Provincial De Castellon | Facila, Lorenzo | Spain | Castellon De La Plana | Castellon De La Plana |
| 436 | Hospital Universitario De Bellvitge | Sabate, Xavier | Spain | Barcelona | Barcelona |
| 437 | Hospital Universitario Ramon Y Cajal | Cruz Jentoft, Alfonso J | Spain | Madrid | Madrid |
| 438 | Hospital Lucus Augusti | Monte Secades, Rafael | Spain | Lugo | Lugo |
| 439 | Hospital De Calde | Veiga Fernandez, Fernando | Spain | Lugo | Lugo |
| 440 | Hospital General Universitario Gregorio Maranon | Vidan, Maria Teresa | Spain | Madrid | Madrid |
| 441 | Hospital Universitario Ramon Y Cajal | Yebra, Miguel | Spain | Madrid | Madrid |
| 442 | Hospital Torrevieja Salud | Mirete Ferrer, Jose Carlos | Spain | Torrevieja | Torrevieja |
| 443 | Hospital Universitario Dr. Peset | Orriach, Maria Dolores | Spain | Valencia | Valencia |
| 444 | Akademiska Sjukhuset | Blomstrom Lundqvist, Carina | Sweden | Uppsala | Uppsala |
| 445 | Sahlgrenska University Hospital/Ostra | Jacobsson, Filip | Sweden | Gothenburg | Gothenburg |
| 446 | Sahlgrenska Universitetssjukhuset/Molndal | Klintberg, Lars | Sweden | Molndal | Molndal |
| 447 | Forskningsenheten Lundby Sjukhus | Ulvenstam, Goran | Sweden | Goteborg | Goteborg |
| 448 | City Heart | Hoglund, Christer | Sweden | Stockholm | Stockholm |
| 449 | Capio S:T G？rans Sjukhus Ab | Maru, Fikru | Sweden | Stockholm | Stockholm |
| 450 | Karolinska University Hospital, Huddinge | Rasmanis, Gundars | Sweden | Stockholm | Stockholm |
| 451 | Sodersjukhuset | Rosenqvist, Marten | Sweden | Stockholm | Stockholm |
| 452 | Far Eastern Memorial Hospital | Chu, Shu-Hsun | China | Taiwan | Taipei |
| 453 | Kaohsiung Medical University Chung-Ho Memorial Hospital | Lai, Wen-Ter | China | Taiwan | Kaohsiung |
| 454 | National Cheng Kung University Hospital | Lin, Li-Jen | China | Taiwan | Tainan |
| 455 | Shin Kong Wu Ho-Su Memorial Hospital | Shyu, Kou-Gi | China | Taiwan | Taipei |
| 456 | Chung-Shan Medical University Hospital | Ueng, Kwo Chang | China | Taiwan | Taichung |
| 457 | Chang Gung Memorial Hospital-Linkou | Wang, Chun-Chieh | China | Taiwan | Taoyuan |
| 458 | Istanbul University Medical Faculty | Adalet, Kamil | Turkey | Istanbul | Istanbul |
| 459 | Kirikkale University Medical Faculty | Ebinc, Haksun | Turkey | Kirikkale | Kirikkale |
| 460 | Suleyman Demirel University Medical Faculty | Ozaydin, Mehmet | Turkey | Isparta | Isparta |
| 461 | Istanbul University Cardiology Institute | Turkoglu, Cengizhan | Turkey | Istanbul | Istanbul |
| 462 | Central City Clinical Hospital #1, Cardiology Department | Bagriy, Andriy | Ukraine | Donetsk | Donetsk |
| 463 | Dnipropetrovsk State Medical Academy, Hospital Therapy #1 | Kuryata, Olexandr | Ukraine | Dnipropetrovsk | Dnipropetrovsk |
| 464 | Kharkiv Med. Acad. Of Postgrad Educ, | Bereznyakov, Igor | Ukraine | Kharkiv | Kharkiv |
| 465 | Mechnikov Inst. Of Microbiology & Immunology Of Ams-Ukraine | Grishyna, Olena | Ukraine | Kharkiv | Kharkiv |
| 466 | Central Clinical Hospital Of Ukrzaliznitsia, | Kraiz, Igor | Ukraine | Kharkiv | Kharkiv |
| 467 | City Clinical Hospital #27, | Prokhorov, Oleksandr | Ukraine | Kharkiv | Kharkiv |
| 468 | Kharkiv Medical Academy Of Postgrad Ed Kzoz City Clin Hosp 8 | Tseluyko, Vira | Ukraine | Kharkiv | Kharkiv |
| 469 | National Medical University | Amosova, Kateryna | Ukraine | Kyiv | Kyiv |
| 470 | Municipal Clinical Hospital #1 | Karpenko, Oleksandr | Ukraine | Kyiv | Kyiv |
| 471 | National Med Acad Of Postgrad Ed P.L.Shupik Region Clin Hosp | Khimion, Lyudmila | Ukraine | Kyiv | Kyiv |
| 472 | National Scientific Ctr-The M.D. Strazhesko Inst. Of Cardio. | Parkhomenko, Alexander | Ukraine | Kyiv | Kyiv |
| 473 | Kyiv Emergency Care Hospital | Rudenko, Leonid | Ukraine | Kyiv | Kyiv |
| 474 | State Institution, Institute Of Gerontology Ams Of Ukraine | Stadnjuk, Leonid | Ukraine | Kyiv | Kyiv |
| 475 | Ninewells Hospital And Medical School | Macwalter, Ronald | United Kingdom | Angus/forfarshire | Dundee |
| 476 | Antrim Area Hospital | Trouton, Thomas G | United Kingdom | Antrim | Antrim |
| 477 | Aberdeen Royal Infirmary | Webster, John | United Kingdom | Aberdeenshire | Aberdeen |
| 478 | Basildon Hospital | Aggarwal, Rajesh | United Kingdom | Essex | Basildon |
| 479 | Chesterfield Royal Hospital Nhs Foundation Trust | Cooke, Justin | United Kingdom | Derbyshire | Chesterfield |
| 480 | Queen'S Hospital | Kadr, Honer | United Kingdom | Essex | Romford |
| 481 | Craigavon Area Hospital | Moriarty, Andrew, J | United Kingdom | Armagh | Craigavon |
| 482 | Colchester General Hospital | Tang, Kare | United Kingdom | Essex | Colchester |
| 483 | Victoria Hospital | Francis, Charles Mark | United Kingdom | Fife | Kirkcaldy |
| 484 | Western Infirmary, Gardiner Institute | Muir, Scott | United Kingdom | Lanarkshire | Glasgow |
| 485 | St George'S University Of London | Savelieva, Irina | United Kingdom | Greater London | London |
| 486 | Blackpool Victoria Hospital | Brack, Michael | United Kingdom | Lancashire | Blackpool |
| 487 | Northwick Park Hospital | Senior, Roxy | United Kingdom | Middlesex | Harrow |
| 488 | Barnsley District Hospital | Albazzaz, Mohammad | United Kingdom | South Yorkshire | Barnsley |
| 489 | Bassetlaw District General Hospital | Alwail, Ali Nagi N | United Kingdom | Nottinghamshire | Worksop |
| 490 | Northampton General Hospital | Davey, Patrick | United Kingdom | Nottinghamshire | Northampton |
| 491 | Royal Alexandra Hospital | Findlay, Iain | United Kingdom | Renfrewshire | Paisley |
| 492 | Forth Valley Royal Hospital | Glen, Stephen | United Kingdom | Stirlingshire | Larbert |
| 493 | City Hospital | Lip, Gregory Y.H | United Kingdom | West Midlands | Birmingham |
| 494 | University Of Newcastle | Thomas, Simon | United Kingdom | Tyne And Wear | Newcastle Upon Tyne |
| 495 | St Richards Hospital | Wong, Yuk-Ki | United Kingdom | West Sussex | Chichester |
| 496 | Southern General Hospital | Murdoch, David | United Kingdom | Lanarkshire | Glasgow |
| 497 | Mobile Heart Specialists, Pc | Bedwell, Noel Wheeler | USA | AL | Mobile |
| 498 | Cardiology Consultants Of Orange County Med. Group Inc | Gogia, Harinder S | USA | CA | Anaheim |
| 499 | Santa Rosa Cardiology | Hunter, John J | USA | CA | Santa Rosa |
| 500 | Desert Med Grp Inc, Dba Desert Oasis Healthcare Med Group | Jardula, Michael F | USA | CA | Palm Springs |
| 501 | North County Internal Medicine | Lafata, John | USA | CA | Vista |
| 502 | Kaiser Permanente Medical Center, West Los Angeles | Lang, Daniel | USA | CA | Los Angeles |
| 503 | San Diego Managed Care Group | Maletz, Louis | USA | CA | San Diego |
| 504 | Yogesh K. Paliwal Md | Paliwal, Yogesh Kumar | USA | CA | Pomona |
| 505 | Southwest Heart | Peart, Brenda C | USA | AZ | Tucscon |
| 506 | University Of California, San Diego | Raisinghani, Ajit | USA | CA | San Diego |
| 507 | Cardiology Associates Of New Haven,Pc | Gerber, Jaime R | USA | CT | Guilford |
| 508 | Stamford Therapeutics Consortium | Heiman, Mark D | USA | CT | Stamford |
| 509 | Washington Va Medical Center | Moore, Hans J | USA | DC | Washington |
| 510 | Research Alliance, Inc. | Amin, Mahesh | USA | FL | Clearwater |
| 511 | The Heart & Vascular Institute Of Florida | Black, Robert A | USA | FL | Dunedin |
| 512 | The Heart Group Of Lee Memorial Health System | Burton, M. Erick | USA | FL | Fort Myers |
| 513 | Cardiovascular Center Of Sarasota | El Shahawy, Mahfouz | USA | FL | Sarasota |
| 514 | Baptist Heart Specialists | Hilton, Thomas C | USA | FL | Jacksonville Beach |
| 515 | Kim A. Klancke, Md | Klanke, Kim A | USA | FL | Daytona Beach |
| 516 | Michael F. Lesser, Md, Facc Osler Medical Inc. | Lesser, Michael | USA | FL | Melbourne |
| 517 | St. Vincent'S Ambulatory Care, Inc | Magnano, Anthony | USA | FL | Jacksonville |
| 518 | Broward General Medical Center | Perloff, David | USA | FL | Fort Lauderdale |
| 519 | Integrated Care Llc D/B/A Cardiovascular Consultants Of S Fl | Schneider, Ricky | USA | FL | Tamarac |
| 520 | Bay Pines Va Healthcare System | Swamy, Mallikarjuna | USA | FL | Bay Pines |
| 521 | The Heart & Vascular Institute Of Florida | Walsh, Ronald Lennox | USA | FL | Dunedin |
| 522 | North Chicago Va Medical Center | Arora, Rohit Romesh | USA | IL | North Chicago |
| 523 | Southeast Regional Research Group | Elkin, Gary | USA | GA | Savannah |
| 524 | Fox Valley Clinical Research Center, Llc | Gill, Santosh K | USA | IL | Aurora |
| 525 | Northeast Georgia Heart Center, Pc | Ramaswamy, Karthik | USA | GA | Gainesville |
| 526 | Atlanta Institute For Medical Research, Inc | Rosenthal, Steven Michael | USA | GA | Atlanta |
| 527 | Southeast Regional Research Group | Surber, Joseph G | USA | GA | Augusta |
| 528 | Hutchinson Clinic, Pa | Brachfeld, Claude | USA | KS | Hutchinson |
| 529 | Dr. Jeffrey Chen | Chen, Yi-Cheng | USA | LA | Lafayette |
| 530 | St Francis Medical Group - Indiana Heart Physicians | Genovely, Harry C | USA | IN | Indianapolis |
| 531 | St. Vincent Medical Group, Inc. | Parr, Kirk L | USA | IN | Indianapolis |
| 532 | Pentucket Medical Associates | Bilazerian, Seth | USA | MA | Haverhill |
| 533 | Michigan Heart And Vascular Specialists | Levanovich, Peter E | USA | MI | Petoskey |
| 534 | Academic Cardiology Associates | Mcgough, Martin F | USA | MI | Rochester Hills |
| 535 | Peninsula Cardiology Associates, P.A. | Nsah, Emmanuel Nchinda | USA | MD | Salisbury |
| 536 | Great Lakes Heart Center Of Alpena | Salacata, Abraham | USA | MI | Alpena |
| 537 | Henry Ford Hospital K-15 | Shah, Vinay | USA | MI | Detroit |
| 538 | Glacier View Cardiology, Pc | Gillespie, Eve L | USA | MT | Kalispell |
| 539 | Tupelo Neurology Clinic, Pa | Graff, Justin C | USA | MS | Tupelo |
| 540 | Kansas City Cardiology Associates, Inc. | Lee, John Kenneth N | USA | MO | Kansas City |
| 541 | Missouri Cardiovascular Specialists | Ravipudi, Sanjeev | USA | MO | Columbia |
| 542 | University Of Missouri | Weachter, Jr., Richard | USA | MO | Columbia |
| 543 | Terry V. Arnold, Md | Arnold, Terry V | USA | NC | Lexington |
| 544 | Sanford Cardiology | Atieh, Mahmoud | USA | NC | Sanford |
| 545 | Capital Cardiology Associates | Benton, Robert | USA | NY | Troy |
| 546 | NYU Hudson Valley Cardiology | Hamroff, Glenn S | USA | NY | Cortlandt Manor |
| 547 | Dr William Kufs | Kufs, William | USA | NY | Saratoga Springs |
| 548 | Hunterdon Cardiovascular Associates | Kutscher, Jr., Austin Harrison | USA | NJ | Flemington |
| 549 | Capital Cardiology Associates | Shah, Parag | USA | NY | Albany |
| 550 | Pinehurst Medical Clinic, Inc | Simpson, Patrick | USA | NC | Pinehurst |
| 551 | Long Island Heart Associates | Smith, Richard H | USA | NY | Mineola |
| 552 | Integris Cardiovascular Physicians | Anderson, Jerome Lyman | USA | OK | Oklahoma City |
| 553 | Davis Heart & Lung Research Institute | Baliga, Ragavendra | USA | OH | Columbus |
| 554 | Ira R. Friedlander, M.D. | Friedlander, Ira Ray | USA | OH | Canton |
| 555 | The Portland Clinic, Llp | Naito, Ronald W | USA | OR | Portland |
| 556 | Hillsboro Cardiology Pc | Promisloff, Steven D | USA | OR | Hillsboro |
| 557 | Oregon Medical Group - Clinical Research | Saxman, Karl A | USA | OR | Eugene |
| 558 | South Oklahoma Heart Research | Tahirkheli, Naeem K | USA | OK | Oklahoma City |
| 559 | Comprehensive Cardiology Consultants | Fields, Ronald H | USA | PA | Langhorne |
| 560 | Lowcountry Medical Group, Llc | Floyd, John | USA | SC | Beaufort |
| 561 | Cardiology Consultants Of Philadelphia | Grena, Paul Gregory | USA | PA | Yardley |
| 562 | Internal Medicine Of Greer | Henry, Iii, W. John | USA | SC | Greer |
| 563 | Grand View - Lehigh Valley Health Services | Hermany, Paul | USA | PA | Sellersville |
| 564 | West Chester Cardiology | Jan, Mian A | USA | PA | West Chester |
| 565 | Medical University Of South Carolina | Zwerner, Peter | USA | SC | Charleston |
| 566 | Knoxville Heart Group | Ayres, Thomas M | USA | TN | Knoxville |
| 567 | Salem Veterans Administration Medical Center | Jarmukli, Nabil F | USA | VA | Salem |
| 568 | Sentara York Clinical Research | Lovell, Charles | USA | VA | Norfolk |
| 569 | Roanoke Heart Institute, Plc | Schmedtje Jr., John Frederick | USA | VA | Roanoke |
| 570 | Walla Walla Clinic | Ball, Eric M | USA | WA | Walla Walla |
| 571 | Wenatchee Valley Medical Center | Kaster, Steven R | USA | WA | Wenatchee |
| 572 | Marshfield Clinic | Vidaillet, Humberto J | USA | WI | Marshfield |
五、伦理委员会信息
| 序号 | 名称 | 审查结论 | 批准日期/备案日期 |
|---|---|---|---|
| 1 | 中国医学科学院阜外心血管病医院伦理委员会 | 修改后同意 | 2008-12-17 |
六、试验状态信息
1、试验状态
进行中 （招募完成）
2、试验人数
| 目标入组人数 | 国内: 256 ； 国际: 5600 ； |
|---|---|
| 已入组人数 | 国内: 登记人暂未填写该信息； 国际: 登记人暂未填写该信息； |
| 实际入组总人数 | 国内: 登记人暂未填写该信息； 国际: 登记人暂未填写该信息； |
3、受试者招募及试验完成日期
| 第一例受试者签署知情同意书日期 | 国内：2009-02-26； 国际：登记人暂未填写该信息； |
|---|---|
| 第一例受试者入组日期 | 国内：登记人暂未填写该信息； 国际：登记人暂未填写该信息； |
| 试验完成日期 | 国内：登记人暂未填写该信息； 国际：登记人暂未填写该信息； |
七、临床试验结果摘要
| 序号 | 版本号 | 版本日期 |
|---|---|---|
| 暂未填写此信息 | ||
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