基本信息
| 登记号 | CTR20221262 | 试验状态 | 进行中 |
|---|---|---|---|
| 申请人联系人 | 徐珊珊 | 首次公示信息日期 | 2022-05-31 |
| 申请人名称 | Mirati Therapeutics, Inc./ 再鼎医药（上海）有限公司/ Patheon Inc. | ||
公示的试验信息
一、题目和背景信息
| 登记号 | CTR20221262 | ||
|---|---|---|---|
| 相关登记号 | |||
| 药物名称 | MRTX849片剂 | ||
| 药物类型 | 化学药物 | ||
| 临床申请受理号 | 企业选择不公示 | ||
| 适应症 | 非小细胞肺癌 | ||
| 试验专业题目 | 一项在携带KRAS G12C突变的既往经治的非小细胞肺癌患者中评价MRTX849对比多西他赛的随机、III期研究 | ||
| 试验通俗题目 | MRTX849对比多西他赛治疗KRAS G12C突变的NSCLC患者的III期研究 | ||
| 试验方案编号 | 849-012 | 方案最新版本号 | 7.0 |
| 版本日期: | 2023-03-24 | 方案是否为联合用药 | 否 |
二、申请人信息
| 申请人名称 | 1 2 3 | ||||
|---|---|---|---|---|---|
| 联系人姓名 | 徐珊珊 | 联系人座机 | 012-61632588 | 联系人手机号 | 15102230909 |
| 联系人Email | shanshan.xu@zailaboratory.com | 联系人邮政地址 | 上海市-上海市-浦东新区金科路4560号金创大厦3号楼8楼 | 联系人邮编 | 200010 |
三、临床试验信息
1、试验目的
比较MRTX849与多西他赛在既往接受过含铂方案和免疫检查点抑制剂治疗的携带有KRAS G12C突变的NSCLC患者中的有效性。
2、试验设计
| 试验分类 | 安全性和有效性 | 试验分期 | III期 | 设计类型 | 平行分组 |
|---|---|---|---|---|---|
| 随机化 | 随机化 | 盲法 | 开放 | 试验范围 | 国际多中心试验 |
3、受试者信息
| 年龄 | 18岁(最小年龄)至 无上限 (最大年龄) | ||
|---|---|---|---|
| 性别 | 男+女 | ||
| 健康受试者 | 无 | ||
| 入选标准 | 1 经组织学或细胞学确诊为存在KRAS G12C突变的NSCLC。 2 既往接受过含铂方案和免疫检查点抑制剂治疗，且治疗后进展 3 可接受多西他赛治疗 4 患有不可切除、局部晚期或转移性疾病。 5 根据RECIST 1.1版，存在可评价或可测量病灶。 6 预期可获得代表性肿瘤样本（原发性或转移性、存档或新采集），用于KRAS G12C突变状态和相关基因改变的中心实验室检测（至少5份切片，最好是15份切片）。 7 年龄≥18岁。 8 预期寿命至少为3个月。 9 既往治疗的不良反应恢复至基线或1级（不包括脱发）。 10 美国东部肿瘤协作组织（ECOG）体能状况评分为0或1。 11 骨髓、器官（肝肾）功能满足方案要求 12 有生育能力的女性（WOCBP）或配偶为WOCBP的男性同意在参与本研究期间和研究治疗终止后6个月内使用避孕方法。 13 完成知情同意过程，包括签署IRB/EC批准的知情同意书（ICF）。 14 愿意遵守临床试验说明和要求。 | ||
| 排除标准 | 1 既往接受过靶向KRAS G12C的药物（例如AMG 510、 sotorasib）治疗。 2 有活动性脑转移或癌性脑膜炎 3 随机化前4周内进行过大手术。 4 存在有可能改变研究治疗吸收或无法吞服药物的肠道疾病史或胃部大手术史。 5 随机化前6个月内有严重的心脏异常或有卒中或短暂性脑缺血发作史 6 入组研究前，需持续使用具有以下任何特征的药物且该药物无法转换为其他替代疗法（见附录2）：已知存在尖端扭转型室性心动过速风险；治疗指数窄的CYP3A底物；CYP3A和/或P-gp的强效诱导剂或抑制剂；BCRP强效抑制剂；质子泵抑制剂。已知人类免疫缺陷病毒（HIV）感染或者急性或慢性乙型肝炎或丙型肝炎感染。请注意，如果出现以下情况，则允许患者入组： 已接受丙型肝炎病毒（HCV）治疗且未检测到病毒载量的患者； 在随机化前接受HIV治疗且至少1个月内未检测到病毒载量，同时接受的是CYP3A4非强效抑制剂稳定给药方案治疗的患者； 接受预防乙肝再激活治疗的乙型肝炎（HBV）患者（[HBsAg阳性且ALT正常和HBV DNA<2000 IU/mL或<10,000拷贝/mL]或[HBsAg阴性和抗HBc阳性]）。 7 已知或怀疑存在其他恶性肿瘤，在疾病评估期间可能被误认为是正在研究的恶性肿瘤。 8 妊娠。随机化前，WOCBP必须有阴性的血清或尿妊娠试验记录。 9 在研究期间或末次研究给药后6个月内进行母乳喂养或计划母乳喂养。 10 研究者认为可能干扰患者提供知情同意的能力、参与研究、或结果解读的任何严重疾病、未控制的并发疾病、精神疾病、活动性或未控制的感染或者其他疾病或病史，包括实验室检查结果。 11 对MRTX849制剂的任何成分过敏。 12 在首次研究给药前30天内接种过活疫苗/减毒疫苗。 | ||
4、试验分组
| 试验药 | 序号 名称 用法 1 中文通用名:MRTX849片剂 英文通用名:MRTX849 Tablets 商品名称:NA 剂型:片剂 规格:200mg/片 用法用量:口服；起始剂量为600mg；BID 用药时程:连续给药；21天为一给药周期 |
|---|---|
| 对照药 | 序号 名称 用法 1 中文通用名:多西他赛注射液 英文通用名:Docetaxel Injection 商品名称:泰索帝 剂型:注射液 规格:0.5ml:20mg 用法用量:静脉滴注；75 mg/m2，静脉滴注1小时；每3周一次。 用药时程:单次给药；21天为一给药周期 |
5、终点指标
| 主要终点指标及评价时间 | 序号 指标 评价时间 终点指标选择 1 无进展生存期（PFS） 随机化至PD或因任何原因死亡（以先发生者为准） 有效性指标 |
|---|---|
| 次要终点指标及评价时间 | 序号 指标 评价时间 终点指标选择 1 安全性：不良事件（AE）的类型、发生率、严重程度、时间、严重性和与研究治疗的关系、实验室检查结果异常和因不良事件而终止研究治疗的患者例数。 研究期间 安全性指标 2 次要有效性终点： - 总生存期（OS）； - 客观缓解率（ORR）； - 缓解持续时间（DOR）； - 1年生存率。 研究期间 有效性指标 3 MRTX849（及其代谢物[如适用]）的血浆PK参数。 MRTX849 治疗期间 有效性指标+安全性指标 4 使用以下量表进行患者报告结局（PRO）评分： - 肺癌症状量表（LCSS）； - 欧洲五维健康量表（EQ-5D-5L）。 随机化至治疗结束 有效性指标+安全性指标 |
6、数据安全监查委员会（DMC）
无
7、为受试者购买试验伤害保险
有
四、研究者信息
1、主要研究者信息
| 1 | 姓名 | 陆舜 | 学位 | 医学博士 | 职称 | 主任医师 |
|---|---|---|---|---|---|---|
| 电话 | 021-22200000-2153 | shunlu_shchest@sina.com | 邮政地址 | 上海市-上海市-上海市淮海西路241号 | ||
| 邮编 | 200030 | 单位名称 | 上海市胸科医院 | |||
2、各参加机构信息
| 序号 | 机构名称 | 主要研究者 | 国家或地区 | 省（州） | 城市 |
|---|---|---|---|---|---|
| 1 | 上海市胸科医院 | 陆舜 | 中国 | 上海市 | 上海市 |
| 2 | 上海市胸科医院 | 姜丽岩 | 中国 | 上海市 | 上海市 |
| 3 | 吉林省肿瘤医院 | 程颖 | 中国 | 吉林省 | 长春市 |
| 4 | 四川省肿瘤医院 | 姚文秀 | 中国 | 四川省 | 成都市 |
| 5 | 四川大学华西医院 | 王永生 | 中国 | 四川省 | 成都市 |
| 6 | 浙江大学医学院附属第一医院 | 周建英 | 中国 | 浙江省 | 杭州市 |
| 7 | 华中科技大学同济医学院附属协和医院 | 董晓荣 | 中国 | 湖北省 | 武汉市 |
| 8 | 河南省人民医院 | 仓顺东 | 中国 | 河南省 | 郑州市 |
| 9 | 河南省肿瘤医院 | 陈丽娟 | 中国 | 河南省 | 郑州市 |
| 10 | 湖北省肿瘤医院 | 胡艳萍 | 中国 | 湖北省 | 武汉市 |
| 11 | 中国医学科学院北京协和医院 | 张力 | 中国 | 北京市 | 北京市 |
| 12 | 浙江省肿瘤医院（浙江省癌症中心） | 范云 | 中国 | 浙江省 | 杭州市 |
| 13 | 南昌大学第一附属医院 | 张伟 | 中国 | 江西省 | 南昌市 |
| 14 | 中国人民解放军总医院 | 胡毅 | 中国 | 北京市 | 北京市 |
| 15 | 复旦大学附属中山医院 | 胡洁 | 中国 | 上海市 | 上海市 |
| 16 | 湖南省肿瘤医院 | 邬麟 | 中国 | 湖南省 | 长沙市 |
| 17 | 中国人民解放军陆军特色医学中心 | 何勇 | 中国 | 重庆市 | 重庆市 |
| 18 | 陆军军医大学西南医院 | 周向东 | 中国 | 重庆市 | 重庆市 |
| 19 | 福建省肿瘤医院 | 庄武 | 中国 | 福建省 | 福州市 |
| 20 | 复旦大学附属肿瘤医院 | 王佳蕾 | 中国 | 上海市 | 上海市 |
| 21 | 徐州市中心医院 | 王翔 | 中国 | 江苏省 | 徐州市 |
| 22 | 北京肿瘤医院 | 赵军 | 中国 | 北京市 | 北京市 |
| 23 | 北京肿瘤医院 | 方健 | 中国 | 北京市 | 北京市 |
| 24 | 江苏省中医院 | 王谦 | 中国 | 江苏省 | 南京市 |
| 25 | 郑州大学第一附属医院 | 李醒亚 | 中国 | 河南省 | 郑州市 |
| 26 | 哈尔滨医科大学附属肿瘤医院 | 于雁 | 中国 | 黑龙江省 | 哈尔滨市 |
| 27 | 南昌大学第二附属医院 | 刘安文 | 中国 | 江西省 | 南昌市 |
| 28 | 厦门大学附属第一医院 | 叶峰 | 中国 | 福建省 | 厦门市 |
| 29 | 柳州市人民医院 | 李竟长 | 中国 | 广西壮族自治区 | 柳州市 |
| 30 | 南京鼓楼医院 | 苗立云 | 中国 | 江苏省 | 南京市 |
| 31 | 辽宁省肿瘤医院 | 马锐 | 中国 | 辽宁省 | 沈阳市 |
| 32 | 南京市第一医院 | 谷伟 | 中国 | 江苏省 | 南京市 |
| 33 | 中国医科大学附属第一医院 | 金波 | 中国 | 辽宁省 | 沈阳市 |
| 34 | 浙江大学医学院附属邵逸夫医院 | 应可净 | 中国 | 浙江省 | 杭州市 |
| 35 | 临沂市肿瘤医院 | 石建华 | 中国 | 山东省 | 临沂市 |
| 36 | 青岛大学附属医院 | 王静 | 中国 | 山东省 | 青岛市 |
| 37 | 山东省肿瘤医院 | 郭其森 | 中国 | 山东省 | 济南市 |
| 38 | 南方医科大学南方医院 | 刘来昱 | 中国 | 广东省 | 广州市 |
| 39 | 广州医科大学附属第一医院 | 周承志 | 中国 | 广东省 | 广州市 |
| 40 | 新乡医学院第一附属医院 | 路平 | 中国 | 河南省 | 新乡市 |
| 41 | Epworth Richmond | Ross Jennens | AUSTRALIA | Victoria | Richmond |
| 42 | Monash Health | Surein Arulananda | AUSTRALIA | Victoria | Heidelberg |
| 43 | Flinders Medical Centre | Christos Karapetis | AUSTRALIA | South Australia | Bedford Park |
| 44 | Princess Alexandra Hospital | Kenneth OByrne | AUSTRALIA | Queensland | Woolloongabba |
| 45 | Concord Repatriation General Hospital | Prunella Blinman | AUSTRALIA | New South Wales | Concord |
| 46 | GenesisCare - North Shore | Nick Pavlakis | AUSTRALIA | New South Wales | St. Leonards |
| 47 | Southern Medical Day Care Centre | Daniel Brungs | AUSTRALIA | New South Wales | Wollongong |
| 48 | The Tweed Hospital | Pawan Bajaj | AUSTRALIA | New South Wales | Tweed Heads |
| 49 | Humanity & Health Clinical Trial Centre | Patrick Lau | 中国香港 | Hong Kong Island | Central |
| 50 | Chonnam National University Hwasun Hospital | Young-Chul Kim | SOUTH KOREA | SOUTH KOREA | Incheon |
| 51 | Korea University Anam Hospital | Yoon Ji Choi | SOUTH KOREA | Seoul Teugbyeolsi [Seoul-T'ukpyolshi] | Seoul |
| 52 | Konkuk University Medical Center | Kye Young Lee | SOUTH KOREA | eoul Teugbyeolsi [Seoul-T'ukpyolshi] | Seoul |
| 53 | Kyungpook National University Chilgok Hospital | Seung Soo Yoo | SOUTH KOREA | Daegu Gwang'yeogsi [Taegu-Kwangyokshi] | Daegu |
| 54 | Seoul National University Bundang Hospital | YuJung Kim | SOUTH KOREA | Gyeonggi-Do | Seongnam-si |
| 55 | Severance Hospital - Yonsei Cancer Center | Hye Ryun Kim | SOUTH KOREA | Seoul Teugbyeolsi [Seoul-T'ukpyolshi] | Seoul |
| 56 | Uniklinikum Salzburg | Michael Studnicka | AUSTRIA | Salzburg | Salzburg |
| 57 | Wiener Gesundheitsverbund - Klinik Floridsdorf | Maximilian Hochmair | AUSTRIA | Vienna | Wien |
| 58 | Medizinische Universit？t Wien | Barbara Kiesewetter-Wiederkehr | AUSTRIA | Vienna | Wien |
| 59 | Centre Hospitalier Universitaire Universite Catholique de Louvain - Site Godinne | Sebahat Ocak | BELGIUM | Namur | Yvoir |
| 60 | Grand H？pital de Charleroi - Notre Dame | Jean-Luc Canon | BELGIUM | Hainaut | Charleroi |
| 61 | Algemeen Ziekenhuis Delta - Campus Rumbeke | Ingel Demedts | BELGIUM | West-Vlaanderen | Roeselare |
| 62 | Algemeen Ziekenhuis Glorieux Ronse | Patrick Alexander | BELGIUM | East Flanders | Ronse |
| 63 | Universitair Ziekenhuis Brussel | Lore Decoster | BELGIUM | Bruxelles-Capitale | Brussels |
| 64 | Algemeen Ziekenhuis Maria Middelares | Paul Germonpré | BELGIUM | Oost-Vlaaderen | Gent |
| 65 | Jessa Ziekenhuis - Campus Virga Jesse | Kristof Cuppens | BELGIUM | Limburg | Hasselt |
| 66 | Vseobecna Fakultni Nemocnice v Praze | Lubo？ Petru？elka | CZECH REPUBLIC | Petr Opalka | Praha 2 |
| 67 | Fakultni nemocnice Bulovka | Petr Opalka | CZECH REPUBLIC | Petr Opalka | Petr Opalka |
| 68 | H？pital Louis Pradel | Micha？l Duruisseaux | FRANCE | Rhone-Alps | Bron |
| 69 | Centre Hospitalier Lyon-Sud | Micha？l Duruisseaux | FRANCE | Rh？ne | Lyon |
| 70 | H？pital de la Croix Rousse | Micha？l Duruisseaux | FRANCE | Rh？ne | Lyon |
| 71 | Centre Georges Fran？ois Leclerc | Coureche Kaderbhai | FRANCE | Bourgogne | Dijon cedex |
| 72 | Centre Hospitalier Universitaire de Caen Normandie | Jeannick Madelaine | FRANCE | Basse-Normandie | Caen cedex 9 |
| 73 | H？pital Morvan | Gilles Robinet | FRANCE | Bretagne | Brest |
| 74 | Hopital Dupuytren | Alain Vergnenegre | FRANCE | Limousin | Limoges cedex |
| 75 | Centre Fran？ois Baclesse | Radj Gervais | FRANCE | Basse-Normandie | Caen Cedex 5 |
| 76 | Institut de Cancerologie Strasbourg Europe | Roland Schott | FRANCE | Alsace | Strasbourg Cedex |
| 77 | Institut de Cancérologie de l’Ouest - Saint-Herblain - Site René Gauducheau | Ludovic Doucet | FRANCE | Loire-Atlantique | Saint Herblain |
| 78 | Institut Paoli-Calmettes | Anne Madroszyk-Flandin | FRANCE | Provence Alpes Cote D-Azure | Marseille |
| 79 | H？pital Arnaud de Villeneuve | Patricia Barre | FRANCE | Hérault | Montpellier |
| 80 | H？pital Arnaud de Villeneuve | Patricia Barre | FRANCE | Hérault | Montpellier |
| 81 | H？pital Arnaud de Villeneuve | Patricia Barre | FRANCE | Hérault | Montpellier |
| 82 | L'H？pital Nord-Ouest (HNO) - Villefranche-sur-Sa？ne | Lionel Falchero | FRANCE | Rh？ne | Gleize |
| 83 | Gustave Roussy | Fabrice Barlesi | FRANCE | Val-de-Marne | Villejuif |
| 84 | Centre Léon Bérard | Maurice Perol | FRANCE | Rhone-Alpes | Lyon |
| 85 | Kliniken Essen-Mitte - Evangelische Huyssens-Stiftung | Daniel Christoph | GERMANY | North-Rhine Westfalia | Essen |
| 86 | Klinikverbund Allg？u gGmbH - Klinik Immenstadt | Christian Schumann | GERMANY | Bayern | Immenstadt |
| 87 | Klinikverbund Allg？u - Klinikum Kempten | Christian Schumann | GERMANY | Bavaria | Kempten |
| 88 | Pius-Hospital Oldenburg | Frank Griesinger | GERMANY | Niedersachsen | Oldenburg |
| 89 | Klinikum Kassel | Martin Wolf | GERMANY | Hessen | Kassel |
| 90 | Asklepios Fachkliniken München-Gauting | Niels Reinmuth | GERMANY | Bayern | Gauting |
| 91 | Krankenhaus Martha-Maria Halle-D？lau | Wolfgang Schütte | GERMANY | Sachsen-Anhalt | Halle (Saale) |
| 92 | Universit？tsklinikum Schleswig-Holstein - Campus Lübeck | Sabine Bohnet | GERMANY | Schleswig-Holstein | Lübeck |
| 93 | Klinikum Esslingen | Martin Faehling | GERMANY | Baden-Wuerttemberg | Esslingen |
| 94 | Evangelisches Krankenhaus Hamm | Thomas Wehler | GERMANY | Nordrhein-Westfalen | Hamm |
| 95 | Zentralklinik Bad Berka | Ekkehard Eigendorff | GERMANY | Thüringen | Bad Berka |
| 96 | München Klinik Bogenhausen | Konrad Kokowski | GERMANY | Bayern | München |
| 97 | Klinikum K？ln-Merheim | Eva Lotte Buchmeier | GERMANY | Nordrhein-Westfalen | K？ln |
| 98 | Klinikum K？ln-Merheim | Eva Lotte Buchmeier | GERMANY | Nordrhein-Westfalen | K？ln |
| 99 | Universit？tsklinikum Bonn | Peter Brossart | GERMANY | Nordrhein-Westfalen | Bonn |
| 100 | Universit？tsmedizin der Johannes Gutenberg-Universit？t Mainz | Jürgen Alt | GERMANY | Rheinland-Pfalz | Mainz |
| 101 | SLK-Kliniken - Fachklinik L？wenstein | Jonas Kuon | GERMANY | Baden-Wuerttemberg | L？wenstein |
| 102 | SLK-Kliniken - Fachklinik L？wenstein | Jonas Kuon | GERMANY | Baden-Wuerttemberg | L？wenstein |
| 103 | Universit？tsklinikum Jena | Susanne Lang | GERMANY | Thuringen | Jena |
| 104 | Universit？tsklinikum Jena | Susanne Lang | GERMANY | Thuringen | Jena |
| 105 | Interbalkan Medical Center of Thessaloniki | Sofia Baka | GREECE | Central Macedonia | Thessaloniki |
| 106 | Hygeia Hospital | Athanassios Argiris | GREECE | Attica | Marousi |
| 107 | Metropolitan Hospital | Helena Linardou | GREECE | Attica | Neo Faliro, Piraeus |
| 108 | University General Hospital of Larissa | Athanasios Kotsakis | GREECE | Thessaly | Larissa |
| 109 | General Hospital for Thoracic Diseases Sotiria | Konstantinos Syrigos | GREECE | Attica | Athens |
| 110 | General Oncology Hospital of Kifisias | Joseph Sgouros | GREECE | Kalyftaki | Nea Kifisia |
| 111 | University General Hospital of Heraklion (PAGNI) | Dimitrios Mavroudis | GREECE | Crete | Heraklion |
| 112 | Metropolitan Hospital | Dimitrios Bafaloukos | GREECE | Attica | Piraeus |
| 113 | Országos Onkológiai Intézet | Tünde Nagy | HUNGARY | Pest | Budapest |
| 114 | Semmelweis Egyetem - Pulmonológiai Klinika | Veronika Müller | HUNGARY | Budapest | Budapest |
| 115 | Mátrai Gyógyintézet | László Urbán | HUNGARY | Heves | Gy？ngy？s |
| 116 | Országos Korányi Pulmonológiai Intézet | Gyula Ostoros | HUNGARY | Pest | Budapest |
| 117 | Istituto Romagnolo per lo Studio dei Tumori | Angelo Delmonte | ITALY | Forlì-Cesena | Marcello Tiseo |
| 118 | Istituto Nazionale Tumori IRCCS Fondazione G. Pascale | Alessandro Morabito | ITALY | Naples | Napoli |
| 119 | Azienda Ospedaliero-Universitaria di Parma | Marcello Tiseo | ITALY | Parma | Parma |
| 120 | ASL 3 Genovese - Ospedale Villa Scassi - Sampierdarena | Manlio Mencoboni | ITALY | Genoa | Genova |
| 121 | Centro di Riferimento Oncologico | Alessandra Bearz | ITALY | Pordenone | Aviano |
| 122 | Centro di Riferimento Oncologico | Silvia Zai | ITALY | Alessandria | Alessandria |
| 123 | Azienda Ospedaliera Universitaria - Università degli Studi della Campania Luigi Vanvitelli | Fortunato Ciardiello | ITALY | Napoli | Napoli |
| 124 | Istituto Europeo di Oncologia | Filippo De Marinis | ITALY | Milan | Milano |
| 125 | Ospedale Vito Fazzi Lecce | Gianpiero Romano | ITALY | Lecce | Lecce |
| 126 | Azienda Ospedaliera di Perugia - Santa Maria della Misericordia | Giulio Metro | ITALY | Perugia | Perugia |
| 127 | Azienda Ospedaliera di Perugia - Santa Maria della Misericordia | Giulio Metro | ITALY | Perugia | Perugia |
| 128 | Azienda Ospedaliera di Perugia - Santa Maria della Misericordia | Giulio Metro | ITALY | Perugia | Perugia |
| 129 | Azienda Ospedaliero - Universitaria - Policlinico - Vittorio Emanuele | Hector Soto Parra | ITALY | Catania | Catania |
| 130 | Fondazione IRCCS - Istituto Nazionale dei Tumori | Giuseppe Lo Russo | ITALY | Milan | Milano |
| 131 | Azienda Ospedaliera di Rilievo Nazionale e di Alta Specializzazione Garibaldi | Roberto Bordonaro | ITALY | Catania | Catania |
| 132 | Istituto di Candiolo - Fondazione del Piemonte per l'Oncologia | Vanesa Gregorc | ITALY | Torino | Candiolo |
| 133 | Azienda Ospedaliera San Giuseppe Moscati - Avellino | Cesare Gridelli | ITALY | Avellino | Avellino |
| 134 | Istituto Nazionale Tumori Regina Elena | Federico Cappuzzo | ITALY | Rome | Roma |
| 135 | Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale San Raffaele | Francesca Ogliari | ITALY | Milan | Milan |
| 136 | Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale San Raffaele | Francesca Ogliari | ITALY | Milan | Milan |
| 137 | Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale San Raffaele | Francesca Ogliari | ITALY | Milan | Milan |
| 138 | Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale San Raffaele | Francesca Ogliari | ITALY | Milan | Milan |
| 139 | Istituto Oncologico Veneto - IRCCS | Giulia Pasello | ITALY | Padova | Padova |
| 140 | Maastricht Universitair Medisch Centrum | Lizza Hendriks | NETHERLANDS | Limburg | Maastricht |
| 141 | Jeroen Bosch Ziekenhuis - Hertogenbosch | Sietske Smulders | NETHERLANDS | North Brabant | 's-Hertogenbosch |
| 142 | Het Nederlands Kanker Instituut | Willemijn Theelen | NETHERLANDS | Noord-Holland | Amsterdam |
| 143 | Isala Zwolle | Johannes Stigt | NETHERLANDS | Overijssel | Zwolle |
| 144 | Amsterdam Universitair Medische Centra - Locatie Vrije Universiteit Medisch Centrum | Sayed Hashemi | NETHERLANDS | North Holland | Amsterdam |
| 145 | St. Antonius Ziekenhuis - Ziekenhuis Utrecht | Elisabeth A (Lisanne) Kastelijn | NETHERLANDS | Utrecht | Utrecht |
| 146 | Hagaziekenhuis Van Den Haag - Leyweg | Henk Codrington | NETHERLANDS | South Holland | Den Haag |
| 147 | Mruk-Med I Sp. z o.o. | Andrzej Mruk | POLAND | Podkarpackie | Rzeszów |
| 148 | MS Pnuemed - Janusz Milanowski, Katarzyna Szmygin-Milanowska Spó？ka Jawna | Janusz Milanowski | POLAND | Lubelskie | Lublin |
| 149 | Narodowy Instytut Onkologii im. Marii Sk？odowskiej-Curie - Państwowy Instytut Badawczy | Dariusz Kowalski | POLAND | Mazowieckie | Warszawa |
| 150 | Pratia MCM Kraków | Aleksandra Grela-Wojewoda | POLAND | Malopolskie | Kraków |
| 151 | Pratia Poznań | Marcin Grabicki | POLAND | Wielkopolskie | Skórzewo |
| 152 | Mazowieckie Centrum Leczenia Chorob Pluc I Gruzlicy | Aleksandra Szczesna | POLAND | Mazowieckie | Otwock |
| 153 | Centro Hospitalar e Universitário de Coimbra | Fernando Jose Santos Barata | PORTUGAL | Coimbra | Coimbra |
| 154 | Hospital de Braga | Beatriz Fernandes | PORTUGAL | Braga | Braga |
| 155 | Hospital da Senhora da Oliveira - Guimar？es | Maria Manuel Figueiredo | PORTUGAL | Guimar？es | Guimar？es |
| 156 | Hospital CUF Porto | Barbara Parente | PORTUGAL | Porto | Porto |
| 157 | Centro Hospitalar de Vila Nova de Gaia/Espinho | Ana Barroso | PORTUGAL | Vila Nova de Gaia | Vila Nova de Gaia |
| 158 | The Champalimaud Centre for the Unknown | Nuno Gil | PORTUGAL | Lisboa | Lisbon |
| 159 | Hospital CUF Descobertas | Maria Encarnacao Macedo Teixeira | PORTUGAL | Lisbon | Lisboa |
| 160 | Instituto Português de Oncologia do Porto Francisco Gentil | Sara Alves | PORTUGAL | Porto | Porto |
| 161 | Budgetary Healthcare Institution of Omsk region “Clinical Oncologic Dispensary” | Anastasia Zimina | RUSSIA | Omsk | Omsk |
| 162 | Budgetary Healthcare Institution of the Udmurt Republic | Sergey Emelyanov | RUSSIA | Izhevsk | Izhevsk |
| 163 | Evimed Oncology Clinic | Oleg Gladkov | RUSSIA | Chelyabinsk | Chelyabinsk |
| 164 | VitaMed - Moscow | Elena Poddubskaya | RUSSIA | Moscow | Moscow |
| 165 | Saint Petersburg Clinical Scientific & Practical Center for Specialized Types of Medical Care (Oncology) | Fedor Moiseenko | RUSSIA | Saint-Petersburg | Saint-Petersburg |
| 166 | EuroCityClinic LLC | Sergey Orlov | RUSSIA | Saint-Petersburg | Saint-Petersburg |
| 167 | Limited Liability Company Medical Sanitary Unit | Vadim Kozlov | RUSSIA | Novosibirsk | Novosibirsk |
| 168 | State Budgetary Institution Healthcare of the Arkhangelsk region | Marina Nechaeva | RUSSIA | Arhangelskaya Oblast | Arhangelsk |
| 169 | Federal State Budgetary Institution “Influenza Research Institute named after N.N. A.A. Smorodintsev | Nina Mosina | RUSSIA | Saint-Petersburg | Saint-Petersburg |
| 170 | State Budgetary Healthcare Institution of the Nizhny Novgorod Region Clinical Diagnostic Center | Anna Valerevna Alyasova | RUSSIA | Nizhniy Novgorod | Nizhniy Novgorod |
| 171 | Republican Clinical Oncological Dispensary of the Ministry of Health of the Republic of Tatarstan named after Professor M.Z. Sigal | Guzel Mukhametshina | RUSSIA | Tatarstan | Kazan |
| 172 | Regional Budgetary Healthcare Institution “G.E. Ostroverkhov Kursk Oncology Scientific and Clinical Center” of the Healthcare Committee of Kursk Region | Igor Lifirenko | RUSSIA | Kursk | Kislino village |
| 173 | FSBI National Medical Research Center of Oncology named after N.N. Blokhin | Elena Reutova | RUSSIA | Moscow | Moscow |
| 174 | Federal State Budget Institution National Medical Research Radiology Center of the Ministry of Healthcare of the Russian Federation (FSBI NMRRC) - P. Hertsen Moscow Oncology Research Institute | Alexander Fedenko | RUSSIA | Kaluga | Obninsk |
| 175 | University Headache Clinic | Evgeny Ledin | RUSSIA | Moscow | Moscow |
| 176 | State Budgetary Institution of Healthcare City Oncology Hospital #62 of The Department of Healthcare of City of Moscow | Daniil Stroyakovskiy | RUSSIA | Moscow | Moscow |
| 177 | Federal State Budgetary Research Institution - Tomsk National Research Medical Center of Russian Academy of Medical Sciences | Victor Goldberg | RUSSIA | Tomsk | Tomsk |
| 178 | First Moscow State Medical University named after I.M. Sechenov | Ali Mudunov | RUSSIA | Moscow | Moscow |
| 179 | First Moscow State Medical University named after I.M. Sechenov | Ali Mudunov | RUSSIA | Moscow | Moscow |
| 180 | State Healthcare Institution Saratov | Svetlana Averyanova | RUSSIA | Saratov | Saratov |
| 181 | The Main Military Clinical Hospital named after Academician N.N. Burdenko | Alexey Smolin | RUSSIA | Moscow | Moscow |
| 182 | State Budgetary Healthcare Institution Samara Regional Clinical Oncology Dispensary | Anna Tarasova | RUSSIA | Samarskaya Oblast | Samara |
| 183 | Saint Petersburg State Healthcare Institution City Clinical Oncology Dispensary | Rashida Orlova | RUSSIA | Saint Petersburg | Saint Petersburg |
| 184 | Universit？tsspital Basel | David K？nig | SWITZERLAND | Basel-Stadt | Basel |
| 185 | Universit？tsspital Basel | David K？nig | SWITZERLAND | Basel-Stadt | Basel |
| 186 | Universit？tsspital Basel | David K？nig | SWITZERLAND | Basel-Stadt | Basel |
| 187 | Spital Simmental-Thun-Saanenland | Christoph Ackermann | SWITZERLAND | Bern | Thun |
| 188 | Kantonsspital Winterthur | Miklos Pless | SWITZERLAND | Zürich | Winterthur |
| 189 | Kantonsspital Graubünden | Michael Mark | SWITZERLAND | Graubünden | Chur |
| 190 | NHS Greater Glasgow and Clyde | Nicola Steele | UNITED KINGDOM | Scotland | Glasgow |
| 191 | University Hospital Birmingham NHS Foundation Trust | Shobhit Baijal | UNITED KINGDOM | England | Birmingham |
| 192 | University College London Hospitals NHS Foundation Trust | Martin Forster | UNITED KINGDOM | England | London |
| 193 | University College London Hospitals NHS Foundation Trust | Martin Forster | UNITED KINGDOM | England | London |
| 194 | East and North Hertfordshire NHS Trust | Andreas Polychronis | UNITED KINGDOM | England | Middlesex |
| 195 | General Hospital of Thessaloniki George Papanikolaou | Theodore Kontakiotis | GREECE | Central Macedonia | Thessaloniki |
| 196 | Anassa General Clinic | Evangelos Voulgaris | GREECE | Thessaly | Volos |
| 197 | BioClinic Thessaloniki | Ioannis Boukovinas | GREECE | Central Macedonia | Thessaloniki |
| 198 | Oncolab Craiova | Dan Stelian Stefan Lungulescu | ROMANIA | Dolj | Craiova |
| 199 | Oncolab Craiova | Dan Stelian Stefan Lungulescu | ROMANIA | Dolj | Craiova |
| 200 | Oncocenter - Oncologie Clinica | Roxana Scheusan | ROMANIA | Timis | Timi？oara |
| 201 | Spitalul Clinic Judetean de Urgenta Sf. Apostol Andrei Constanta | Laura Mazilu | ROMANIA | Constan？a | Constan？a |
| 202 | Ovidius Clinical Hospital | Laura Mazilu | ROMANIA | Constan？a | Constan？a |
| 203 | Cha Bundang Medical Center | Joo-Hang Kim | SOUTH KOREA | Gyeonggi-Do | Seongnam-si |
| 204 | Catholic University of Korea Saint Vincent's Hospital | Byoung Yong Shim | SOUTH KOREA | Gyeonggi-do | Suwon-si |
| 205 | Pusan National University Hospital | Mi-Hyun Kim | SOUTH KOREA | Busan Gwang'yeogsi [Pusan-Kwangyokshi] | Busan |
| 206 | Pusan National University Hospital | Mi-Hyun Kim | SOUTH KOREA | Busan Gwang'yeogsi [Pusan-Kwangyokshi] | Busan |
| 207 | Keimyung University Dongsan Hospital | Keon Uk Park | SOUTH KOREA | Gyeongsangbugdo [Kyongsangbuk-do] | Daegu |
| 208 | Valley Medical Group - Westwood Medical | Eli Kirshner | UNITED STATES | New Jersey | Paramus |
| 209 | Franciscan Health Munster | Harsha Ranganath | UNITED STATES | Indiana | Munster |
| 210 | Holy Name Medical Center | Yadyra Rivera | UNITED STATES | New Jersey | Teaneck |
| 211 | Hospital Clinic de Barcelona | Nuria Vi？olas | SPAIN | Barcelona | Barcelona |
| 212 | Hospital Clínico San Carlos | Carlos Aguado De La Rosa | SPAIN | Madrid | Madrid |
| 213 | Hospital Universitario Son Espases | Aitor Azkárate Martínez | SPAIN | Balearic Islands | Palma de Mallorca |
| 214 | Hospital Clinico Universitario Lozano Blesa | Maria Dolores Isla Casado | SPAIN | Zaragoza | Zaragoza |
| 215 | Hospital Universitario Marques de Valdecilla | Marta Lopez-Brea Piqueras | SPAIN | Cantabria | Santander |
| 216 | Hospital Universitari i Politècnic La Fe | Oscar Jose Juan Vidal | SPAIN | Valencia | Valencia |
| 217 | Hospital Universitario Ramón y Cajal | Maria Pilar Garrido Lopez | SPAIN | Madrid | Madrid |
| 218 | Complejo Hospitalario Ruber Juan Bravo | Araceli Priego Priego | SPAIN | Madrid | Madrid |
| 219 | Hospital Regional Universitario de Málaga - Hospital Civil | Hospital Regional Universitario de Málaga - Hospital Civil | SPAIN | Málaga | Málaga |
| 220 | Hospital Universitario Fundación Jiménez Díaz | Manuel Dómine Gomez | SPAIN | Madrid | Madrid |
| 221 | Hospital Germans Trias i Pujol | Enric Carcereny Costa | SPAIN | Barcelona | Badalona |
| 222 | Clínica Universidad de Navarra - Madrid | Gonzalo Fernández Hinojal | SPAIN | Madrid | Madrid |
| 223 | Clínica Universidad de Navarra - Madrid | Gonzalo Fernández Hinojal | SPAIN | Madrid | Madrid |
| 224 | Clinica Universidad de Navarra - Pamplona | Gonzalo Fernández Hinojal | SPAIN | Navarre | Pamplona |
| 225 | Clinica Universidad de Navarra - Pamplona | Gonzalo Fernández Hinojal | SPAIN | Madrid | Madrid |
| 226 | Hospital Universitari Vall d'Hebrón | Enriqueta Felip Font | SPAIN | Barcelona | Barcelona |
| 227 | Complejo Hospitalario Universitario A Coru？a | Maria Rosario Garcia Campelo | SPAIN | La Coru？a | A Coru？a |
| 228 | Hospital Universitari Dexeus | Andres Aguilar Hernandez | SPAIN | Barcelona | Barcelona |
| 229 | Hospital Universitario Lucus Augusti | Sergio Vazquez Estevez | SPAIN | Lugo | Lugo |
| 230 | Hospital Universitario Virgen de las Nieves | Javier Valdivia Bautista | SPAIN | Granada | Granada |
| 231 | Hospital Universitario Virgen de las Nieves | Javier Valdivia Bautista | SPAIN | Granada | Granada |
| 232 | Hospital Universitario Reina Sofía | Isidoro Carlos Barneto Aranda | SPAIN | Córdoba | Córdoba |
| 233 | Consorci Hospital General Universitari de València | Ana Blasco Cordellat | SPAIN | València | València |
| 234 | Hospital Universitario Virgen del Rocío | Maria De Los Reyes Bernabe Caro | SPAIN | Sevilla | Sevilla |
| 235 | Radboud Universitair Medisch Centrum | Berber Piet | NETHERLANDS | Gelderland | Nijmegen |
| 236 | Radboud Universitair Medisch Centrum | Berber Piet | NETHERLANDS | Gelderland | Nijmegen |
| 237 | Universitair Medisch Centrum Utrecht | Anne Van Lindert | NETHERLANDS | Utrecht | Utrecht |
| 238 | Albert Schweitzer Ziekenhuis - Dordwijk | Eric Van Thiel | NETHERLANDS | South Holland | Dordrecht |
| 239 | Centro Hospitalar de Entre？o？Douro e Vouga | Joana Godinho | PORTUGAL | Aveiro | Santa Maria Da Feira |
| 240 | Centro Hospitalar de Entre？o？Douro e Vouga | Joana Godinho | PORTUGAL | Aveiro | Santa Maria Da Feira |
| 241 | Instituto Portugues De Oncologia De Lisboa Francisco Gentil | Telma Sequeira | PORTUGAL | Lisboa | Lisbon |
| 242 | Hospital Particular do Algarve - Gambelas - Faro | André Oliveira | PORTUGAL | Faro | Gambelas |
| 243 | Hospital Garcia de Orta | Miguel Lopes | PORTUGAL | Setúbal | Almada |
| 244 | Centro Hospitalar de Setúbal | Filipa Macedo | PORTUGAL | Setúbal | Setúbal |
| 245 | Centro Hospitalar de Setúbal | Filipa Macedo | PORTUGAL | Setúbal | Setúbal |
| 246 | LungenClinic Grosshansdorf | Martin Reck | GERMANY | Schleswig-Holstein | Gro？hansdorf |
| 247 | Universit？tsklinikum Freiburg | Cornelius Waller | GERMANY | Baden-Württemberg | Freiburg |
| 248 | Universit？tsklinikum Gie？en und Marburg - Gie？en | Thomas Wehler | GERMANY | Hessen | Gie？en |
| 249 | Evangelische Lungenklinik Berlin | Christian Grohé | GERMANY | Berlin | Berlin |
| 250 | Universit？tsmedizin Mannheim | Melanie Janning | GERMANY | Baden-Württemberg | Mannheim |
| 251 | H？pital Michallon | Denis Moro-Sibilot | FRANCE | Rhone-Alpes | La Tronche |
| 252 | Centre de Lutte contre le Cancer - Centre Antoine Lacassagne | Nicolas Martin | FRANCE | Provence Alpes Cote D-Azur | Nice Cedex 2 |
| 253 | Centre de Lutte contre le Cancer - Centre Antoine Lacassagne | Nicolas Martin | FRANCE | Provence Alpes Cote D-Azur | Nice Cedex 2 |
| 254 | H？pital Nord de Marseille | Pascale Tomasini | FRANCE | Provence Alpes Cote d′Azur | Marseille |
| 255 | H？pital Nord de Marseille | Pascale Tomasini | FRANCE | Rhone-Alpes | Saint-Priest-en-Jarez |
| 256 | Instytut MSF | Ewa Kalinka | POLAND | Lódzkie | ？ód？ |
| 257 | Azienda Ospedaliera Universitaria Integrata Verona | Sara Pilotto | ITALY | Verona | Verona |
| 258 | Fejér Megyei Szent Gy？rgy Egyetemi Oktató Kórház | Zsolt Pápai-Székely | HUNGARY | Fejer County | Székesfehérvár |
| 259 | Specjalistyczna Praktyka Lekarska Slawomir Mandziuk | S？awomir Mańdziuk | POLAND | Lubelskie | Lublin |
| 260 | Hospital del Mar - Parc de Salut Mar | Edurne Arriola Aperribay | SPAIN | Barcelona | Barcelona |
| 261 | Azienda Ospedaliero - Universitaria Careggi | Lorenzo Antonuzzo | ITALY | Florence | Firenze |
| 262 | Békés Megyei K？zponti Kórház - Pándy Kálmán Tagkórház | Ibolya Vendrey-Laczó | HUNGARY | Bekes | Gyula |
| 263 | Institut Català d'Oncologia Girona (ICO Girona) | Joaquim Bosch Barrera | SPAIN | Girona | Girona |
| 264 | Azienda Socio Sanitaria Territoriale (ASST) degli Spedali Civili di Brescia | Salvatore Grisanti | ITALY | Brescia | Brescia |
| 265 | Azienda Ospedaliera Ospedali Riuniti Marche Nord | Rita Chiari | ITALY | Pesaro e Urbino | Pesaro |
| 266 | Ospedale Santa Maria delle Croci di Ravenna | Chiara Bennati | ITALY | Emilia-Romagna | Ravenna |
| 267 | Hospital General Universitario Dr. Balmis | Bartomeu Massuti Sureda | SPAIN | Alicante | Alicante |
| 268 | Azienda Ospedaliero-Universitaria Maggiore della Carità di Novara | Federica Biello | ITALY | Novara | Novara |
| 269 | Azienda Ospedaliero-Universitaria Maggiore della Carità di Novara | Federica Biello | ITALY | Novara | Novara |
| 270 | Wojskowy Instytut Medyczny | Renata Duchnowska | POLAND | Mazowieckie | Warszawa |
| 271 | Hospital de León | Soledad Medina Valdivieso | SPAIN | León | León |
| 272 | Hospital Universitario Cruces | Raquel Casas Cornejo | SPAIN | Biscay | Barakaldo |
| 273 | Franciscan Health Munster | Yameen Rashid | UNITED STATES | Indiana | Munster |
| 274 | Umberto I - Policlinico di Roma | Alain Gelibter | ITALY | Roma | Roma |
| 275 | Umberto I - Policlinico di Roma | Alain Gelibter | ITALY | Roma | Roma |
| 276 | NEXT Virginia | Alexander Spira | UNITED STATES | Virginia | Fairfax |
| 277 | Mount Sinai Comprehensive Cancer Center | Mike Cusnir | UNITED STATES | Florida | Aventura |
| 278 | Northwest Georgia Oncology Centers Wellstar - Marietta | Steven McCune | UNITED STATES | Georgia | Marietta |
| 279 | Kettering Cancer Center - Kettering Health Network | Priya Jain | UNITED STATES | Ohio | Kettering |
| 280 | Boca Raton Clinical Research (BRCR) Global USA - Plantation | Harshad Amin | UNITED STATES | Florida | Plantation |
| 281 | St. Vincent Healthcare Cancer Centers of Montana | Patrick Cobb | UNITED STATES | Montana | Billings |
| 282 | Sisters of Charity of Leavenworth Health St. Mary's | Alicia Swink | UNITED STATES | Colorado | Grand Junction |
| 283 | 21st Century Oncology of Jacksonville - North Lee Street | Troy Guthrie Jr. | UNITED STATES | Florida | Jacksonville |
| 284 | Frederick Health | Elhamy Eskander | UNITED STATES | Maryland | Frederick |
| 285 | Providence Medical Group - Santa Rosa | Ian Anderson | UNITED STATES | California | Santa Rosa |
| 286 | Rocky Mountain Cancer Centers - Lone Tree | Robert Jotte | UNITED STATES | Colorado | Lone Tree |
| 287 | USOR - Rocky Mountain Cancer Centers - Aurora | Robert Jotte | UNITED STATES | Colorado | Aurora |
| 288 | USOR - Rocky Mountain Cancer Centers - Boulder | Robert Jotte | UNITED STATES | Colorado | Boulder |
| 289 | USOR - Rocky Mountain Cancer Centers - Centennial | Robert Jotte | UNITED STATES | Colorado | Centennial |
| 290 | USOR - Rocky Mountain Cancer Centers - Colorado Springs | Robert Jotte | UNITED STATES | Colorado | Colorado Springs |
| 291 | USOR - Rocky Mountain Cancer Center - Denver - Midtown | Robert Jotte | UNITED STATES | Colorado | Denver |
| 292 | USOR - Rocky Mountain Cancer Centers - Lakewood | Robert Jotte | UNITED STATES | Colorado | Lakewood |
| 293 | USOR - Rocky Mountain Cancer Centers - Littleton | Robert Jotte | UNITED STATES | Colorado | Littleton |
| 294 | USOR - Rocky Mountain Cancer Centers - Longmont | Robert Jotte | UNITED STATES | Colorado | Longmont |
| 295 | USOR - Rocky Mountain Cancer Centers - Pueblo | Robert Jotte | UNITED STATES | Colorado | Pueblo |
| 296 | USOR - Rocky Mountain Cancer Centers - Denver - Rose Medical Center Campus | Robert Jotte | UNITED STATES | Colorado | Denver |
| 297 | USOR - Rocky Mountain Cancer Centers - Thornton | Robert Jotte | UNITED STATES | Colorado | Thornton |
| 298 | Illinois Cancer Specialists - Niles | David Hakimian | UNITED STATES | Illinois | Niles |
| 299 | USOR - Illinois Cancer Specialists - Arlington Heights | David Hakimian | UNITED STATES | Illinois | Arlington Heights |
| 300 | Texas Oncology Dallas Fort Worth West (DFFW) - Arlington Cancer Center North | John Adams | UNITED STATES | Texas | Arlington |
| 301 | USOR - Texas Oncology Dallas Fort Worth West (DFFW) - Arlington South | John Adams | UNITED STATES | Texas | Arlington |
| 302 | TOI Clinical Research (ICIR) | Omkar Marathe | UNITED STATES | California | Whittier |
| 303 | TOI Clinical Research (ICIR) | Omkar Marathe | UNITED STATES | California | Whittier |
| 304 | The Oncology Institute of Hope & Innovation - Whittier | Merrill Shum | UNITED STATES | California | Whittier |
| 305 | The Oncology Institute of Hope & Innovation - Long Beach | Merrill Shum | UNITED STATES | California | Long Beach |
| 306 | The Oncology Institute of Hope & Innovation - Santa Ana | Merrill Shum | UNITED STATES | California | Santa Ana |
| 307 | The Oncology Institute of Hope & Innovation - Glendale | Merrill Shum | UNITED STATES | California | Glendale |
| 308 | City of Hope - Huntington Beach | Danny Nguyen | UNITED STATES | California | Duarte |
| 309 | City of Hope Irvine - Sand Canyon | Danny Nguyen | UNITED STATES | California | Duarte |
| 310 | City of Hope Newport Beach Lido | Danny Nguyen | UNITED STATES | California | Duarte |
| 311 | City of Hope Torrance | Danny Nguyen | UNITED STATES | California | Duarte |
| 312 | City of Hope - Long Beach Elm | Danny Nguyen | UNITED STATES | California | Duarte |
| 313 | Tulane University | Mark Sides | UNITED STATES | Louisiana | New Orleans |
| 314 | University Cancer and Blood Center - Athens - Clarke County Medical Oncology Clinic | Gustavo Westin | UNITED STATES | Georgia | Athens |
| 315 | Cancer Center of Kansas - Wichita - Heritage Plaza | Shaker Dakhil | UNITED STATES | Kansas | Wichita |
| 316 | Cancer Center of Kansas - Medical Arts Tower | Shaker Dakhil | UNITED STATES | Kansas | Wichita |
| 317 | Cancer Center of Kansas - Chanute - Ashley Clinic | Shaker Dakhil | UNITED STATES | Kansas | Chanute |
| 318 | Cancer Center of Kansas - Dodge City | Shaker Dakhil | UNITED STATES | Kansas | Dodge City |
| 319 | Cancer Center of Kansas - Susan B. Allen Memorial Hospital | Shaker Dakhil | UNITED STATES | Kansas | El Dorado |
| 320 | Cancer Center of Kansas - Independence Healthcare Center | Shaker Dakhil | UNITED STATES | Kansas | Independence |
| 321 | Cancer Center of Kansas - Kingman Hospital | Shaker Dakhil | UNITED STATES | Kansas | Kingman |
| 322 | Cancer Center of Kansas - Southwest Medical Center | Shaker Dakhil | UNITED STATES | Kansas | Liberal |
| 323 | Cancer Center of Kansas - McPherson Memorial Hospital | Shaker Dakhil | UNITED STATES | Kansas | McPherson |
| 324 | Cancer Center of Kansas - Newton Medical Center | Shaker Dakhil | UNITED STATES | Kansas | Newton |
| 325 | Cancer Center of Kansas - Labette Health | Shaker Dakhil | UNITED STATES | Kansas | Parsons |
| 326 | Cancer Center of Kansas - Pratt Regional Medical Center | Shaker Dakhil | UNITED STATES | Kansas | Pratt |
| 327 | Cancer Center of Kansas - Salina | Shaker Dakhil | UNITED STATES | Kansas | Salina |
| 328 | Cancer Center of Kansas - Sumner County Family Care Center | Shaker Dakhil | UNITED STATES | Kansas | Wellington |
| 329 | Cancer Center of Kansas - Winfield Health Care Center | Shaker Dakhil | UNITED STATES | Kansas | Winfield |
| 330 | Goshen Center for Cancer Care | Ebenezer Kio | UNITED STATES | Indiana | Goshen |
| 331 | Froedtert Hospital | Smitha Menon | UNITED STATES | Wisconsin | Milwaukee |
| 332 | Central Care Cancer Center - Bolivar | Leonid Shunyakov | UNITED STATES | Missouri | Bolivar |
| 333 | Lifespan Cancer Institute - Rhode Island Hospital | Christopher Azzoli | UNITED STATES | Rhode Island | Providence |
| 334 | Baptist Health Lexington | Firas Badin | UNITED STATES | Kentucky | Lexington |
| 335 | Weill Cornell Medicine | Giuseppe Giaccone | UNITED STATES | New York | New York |
| 336 | Oregon Oncology Specialists | Janelle Meyer | UNITED STATES | Oregon | Salem |
| 337 | Holy Cross Health Fort Lauderdale - Holy Cross Hospital | David Drew | UNITED STATES | Florida | Fort Lauderdale |
| 338 | Orlando Health University of Florida Health Cancer Center - Head and Neck Center | Tirrell Johnson | UNITED STATES | California | San Diego |
| 339 | St？dtisches Klinikum Braunschweig | Miriam Ahlborn | GERMANY | Niedersachsen | Braunschweig |
| 340 | St？dtisches Klinikum Braunschweig | Miriam Ahlborn | GERMANY | Niedersachsen | Braunschweig |
| 341 | Monash Health | Muhammad Alamgeer | AUSTRALIA | Victoria | Clayton |
| 342 | Van Yüzüncü Y？l üniversitesi Dursun Odaba？ T？p Merkezi | Mehmet Naci Aldemir | TURKEY | Van | Tu？ba |
| 343 | T.C. Sa？l？k Bakanl？？？ Kütahya Sa？l？k Bilimleri üniversitesi Evliya ？elebi E？itim Ve Ara？t？rma Hastanesi | Mehmet Aliustaoglu | TURKEY | Kütahya | Kutahya |
| 344 | Alexandroupolis University General Hospital | Kyriakos Amarantidis | GREECE | Eastern Macedonia and Thrace | Alexandroupoli |
| 345 | Multiprofile Hospital For Active Treatment | Adriana Andreeva | BULGARIA | Sofia City | Sofia |
| 346 | University General Hospital for Active Treatment | Tatyana Apostolova | BULGARIA | Plovdiv | Plovdiv |
| 347 | Saint Savvas Anticancer - Oncological Hospital of Athens | Alexandros Ardavanis | GREECE | Attica | Athens |
| 348 | Healthycore - Israel-Georgia Medical Research Clinic Helsikor | Ekaterine Arkania | GEORGIA | Tbilisi | T'bilisi |
| 349 | Izmir Ekonomi Universitesi Medical Point Hastanesi | Cagatay Arslan | TURKEY | Izmir | Izmir |
| 350 | Necmettin Erbakan üniversitesi Meram T？p Fakültesi Hastanesi | Mehmet Artac | TURKEY | Konya | Konya |
| 351 | Centre Hospitalier Intercommunal Toulon - La Seyne sur Mer | Clarisse Audigier-Valette | FRANCE | Provence-Alpes-C？te d'Azur | Toulon cedex |
| 352 | CancerCare Manitoba - McDermot and Urgent Care Site | Shantanu Banerji | CANADA | Manitoba | Winnipeg |
| 353 | Spitalul Sfantul Constantin | Eugeniu Banu | ROMANIA | Brasov | Brasov |
| 354 | Tbilisi Central Hospital | Nazi Barishvili | GEORGIA | Tbilisi | Tbilisi |
| 355 | Complejo Asistencial Universitario de Burgos - Hospital Universitario de Burgos | Cristina Bayona Antón | SPAIN | Burgos | Burgos |
| 356 | H？pital Foch | Jaafar Bennouna-Louridi | FRANCE | ？le-de-France | Suresnes |
| 357 | Institut Jules Bordet | Thierry Berghmans | BELGIUM | Bruxelles-Capitale | Bruxelles-Capitale |
| 358 | Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastirma Hastanesi | Omur Berna Cakmak Oksuzoglu | TURKEY | Ankara | Yenimahalle |
| 359 | Bagcilar Medipol Mega Universite Hastanesi | Ahmet Bilici | TURKEY | ？stanbul | ？stanbul |
| 360 | H？pital Notre-Dame | Normand Blais | CANADA | Quebec | Montreal |
| 361 | Szent Borbála Kórház | Csaba B？cskei | HUNGARY | Komárom-Esztergom | Tatabánya |
| 362 | Mazowiecki Szpital Wojewódzki im. ？w. Jana Paw？a II w Siedlcach | Lubomir Bodnar | POLAND | Mazowieckie | Siedlce |
| 363 | PA Hertzen Moscow Oncology Research Institute | Larisa Bolotina | RUSSIA | Moscow | Moskva |
| 364 | FSBI National Medical Research Center of Oncology named after N.N. Blokhin | Valery Breder | RUSSIA | Moscow | Moscow |
| 365 | Wielkopolskie Centrum Pulmonologii i Torakochirurgii im. Eugenii i Janusza Zeylandów | Maciej Bryl | POLAND | Wielkopolskie | Poznań |
| 366 | Mount Sinai Hospital - Canada | Ronald Burkes | CANADA | Ontario | Toronto |
| 367 | Kocaeli üniversitesi Ara？t？rma ve Uygulama Hastanesi | Devrim Cabuk | TURKEY | Kocaeli | Izmit Kocaeli |
| 368 | Ankara üniversitesi T？p Fakültesi - Cebeci Ara？t？rma ve Uygulama Hastanesi | Filiz Cay Senler | TURKEY | Ankara | Mamak |
| 369 | William Osler Health System - Brampton Civic Hospital | Parneet Cheema | CANADA | Ontario | Brampton |
| 370 | Institute of Clinical Oncology - Tbilisi | Nino Chichua | GEORGIA | Tbilisi | Tbilisi |
| 371 | Evex Hospitals - Caraps Medline | Nana Chikhladze | GEORGIA | Tbilisi | Tbilisi |
| 372 | Hong Kong Sanatorium and Hospital | Daniel Chua | 中国香港 | HONG KONG ISLAND | Happy Valley |
| 373 | Trakya üniversitesi Sa？l？k Ara？t？rma ve Uygulama Merkezi | Irfan Cicin | TURKEY | Edirne | Edirne |
| 374 | T.C. Saglik Bakanligi Adana Sehir Egitim ve Arastirma Hastanesi | Timucin Cil | TURKEY | Adana | Seyhan |
| 375 | University Hospital Limerick | Linda Coate | IRELAND | Limerick | Limerick |
| 376 | Hospital Regional Universitario de Málaga - Hospital Civil | Manuel Cobo Dols | SPAIN | Málaga | Málaga |
| 377 | Jewish General Hospital - Lady Davis Institute for Medical Research | Victor Cohen | CANADA | Québec | Montreal |
| 378 | Akdeniz üniversitesi Hastanesi | Hasan Senol Coskun | TURKEY | Antalya | Antalya |
| 379 | Jász-Nagykun-Szolnok Megyei Hetényi Géza Kórház-Rendel？intézet | Tibor Csoszi | HUNGARY | Jasz-Nagykun-Szolnok | Szolnok |
| 380 | Uluda？ üniversitesi T？p Fakültesi Hastanesi | Erdem Cubukcu | TURKEY | Bursa | Bursa |
| 381 | Szpitale Pomorskie Spó？ka Z Ograniczon？ Odpowiedzialno？ci？ | Iwona Danielewicz | POLAND | Pomorskie | Gdynia |
| 382 | Complex Oncology Center - Burgas | Hristo Dechev | BULGARIA | Burgas | Burgas |
| 383 | Memorial Ankara Hastanesi | Umut Demirci | TURKEY | Ankara | Ankara |
| 384 | Saint Savvas Anticancer - Oncological Hospital of Athens | Stamatina Demiri | GREECE | Attica | Athens |
| 385 | Algemeen Ziekenhuis Groeninge - Campus Kennedylaan | Sofie Derijcke | BELGIUM | West-Vlaanderen | Kortrijk |
| 386 | Institute of Clinical Oncology - Tbilisi | Eka Dgebuadze | GEORGIA | Tbilisi | Tbilisi |
| 387 | Erasmus Medisch Centrum | Anne-Marie Dingemans | NETHERLANDS | Zuid-Holland | Rotterdam |
| 388 | Acibadem Adana Hospital | Umut D？sel | TURKEY | Adana | Seyhan |
| 389 | Pamukkale üniversitesi T？p Fakültesi | Gamze Gokoz Do？u | TURKEY | Denizli | Pamukkale |
| 390 | Masarykova nemocnice v ústí nad Labem | Daniel Dolezal | CZECH REPUBLIC | ústí nad Labem | ústí nad Labem |
| 391 | Galway Clinic | Paul Donnellan | IRELAND | Galway | Galway |
| 392 | Interbalkan Medical Center of Thessaloniki | Christos Emmanouilides | GREECE | Central Macedonia | Thessaloniki |
| 393 | Acibadem Maslak Hastanesi | Yesim Eralp | TURKEY | Istanbul | Sariyer |
| 394 | VM Medical Park Samsun Hastanesi | Dilek Erdem | TURKEY | Samsun | Atakum |
| 395 | Hacettepe üniversitesi Kanser Enstitüsü | Mustafa Erman | TURKEY | Ankara | Ankara |
| 396 | Ballarat Regional Integrated Cancer Center | Wasek Faisal | AUSTRALIA | Victoria | Ballarat |
| 397 | Euromedica General Clinic - Thessaloniki | George Fountzilas | GREECE | Thessaloniki | Thessaloniki |
| 398 | University Specialized Hospital for Active Treatment in Oncology EAD - Sofia | Alexander Gerasimov | BULGARIA | Sofya | Sofia |
| 399 | The Alfred | Sanjeev Gill | AUSTRALIA | Victoria | Melbourne |
| 400 | Ege üniversitesi T？p Fakültesi Hastanesi | Tuncay Goksel | TURKEY | Izmir | Bornova |
| 401 | Hospital Universitario Vithas Madrid La Milagrosa | Jose Luis Gonzalez-Larriba | SPAIN | Madrid | Madrid |
| 402 | Krankenhaus Nordwest | Thorsten Oliver G？tze | GERMANY | Hessen | Frankfurt am Main |
| 403 | T.C. Saglik Bakanligi - Istanbul Il Saglik Mudurlugu - Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi | Mahmut Gumus | TURKEY | Ankara | Alt？nda？ |
| 404 | Sakarya üniversitesi | Ilhan Hacibekiroglu | TURKEY | Sakarya | Adapazar？ |
| 405 | Klinikum Chemnitz | Stefan Hammerschmidt | GERMANY | Sachsen | Chemnitz |
| 406 | HaysMed | Mark Hancock | UNITED STATES | Florida | Fort Lauderdale |
| 407 | Tom Baker Cancer Centre | Desiree Hao | CANADA | Alberta | Calgary |
| 408 | In？nü üniversitesi Turgut ？zal T？p Merkezi | Hakan Harputluoglu | TURKEY | Malatya | Malatya |
| 409 | Allan Blair Cancer Centre | Mussawar Iqbal | CANADA | Saskatchewan | Regina |
| 410 | Acibadem Bursa Hastanesi | Ozkan Kanat | TURKEY | Bursa | Bursa |
| 411 | Dicle üniversitesi T？p Fakültesi | Muhammet Ali Kaplan | TURKEY | Diyarbakir | Sur |
| 412 | N.N. Petrov National Medical Research Center of Oncology | Alexey Karachun | RUSSIA | St Petersburg | Pesochny |
| 413 | Ankara Il Saglik Mudurlugu SBU Gulhane Egitim Ve Arastirma Hastanesi | Nuri Karadurmus | TURKEY | Ankara | Etlik |
| 414 | Przychodnia Lekarska KOMED Roman Karaszewski | Boguslawa Karaszewska Przychodnia Lekarska KOMED Roman Karaszewski | POLAND | Wielkopolskie | Konin |
| 415 | Mater Misericordiae University Hospital | Deirdre Kelly | IRELAND | Dublin | Dublin |
| 416 | Mater Misericordiae University Hospital | Deirdre Kelly | IRELAND | Ontario | Toronto |
| 417 | Liv Hospital Ankara | Saadettin Kilickap | TURKEY | Ankara | Ankara |
| 418 | Hallym University Sacred Heart Hospital | Ho Young Kim | SOUTH KOREA | Gyeonggido [Kyonggi-do] | Anyang-Si |
| 419 | Geongsang National University Changwon Hospital | Hoon-Gu Kim | SOUTH KOREA | Gyeongsangnamdo [Kyongsangnam-do] | Changwon |
| 420 | Veszprém Megyei Tüd？gyógyintézet | Zsolt Király | HUNGARY | Veszprem | Farkasgyep？ |
| 421 | State Budgetary Healthcare Institution | Dmitry Kirtbaya | RUSSIA | Krasnodar | Sochi |
| 422 | State Budgetary Institution of Healthcare of the Yaroslavl Region Regional Clinical Oncological Hospital | Nikolay Kislov | RUSSIA | Yaroslavl | Yaroslavl |
| 423 | Medical University Reaviz | Mikhail Kopp | RUSSIA | Samarskaya Oblast | Samara |
| 424 | Fakultni nemocnice v Motole | Leona Koubkova | CZECH REPUBLIC | Prague | Praha 5 |
| 425 | Multiprofile Hospital for Active Treatment Serdika | Krassimir Koynov | BULGARIA | Sofia | Sofia City |
| 426 | Kirov Regional State Clinical Budgetary Healthcare Institution - Center of Oncology and Medical Radiology | Alexey Kuzmin | RUSSIA | Tatarstan | Kazan |
| 427 | H？mato-Onkologie Hamburg Prof. Laack und Partner | Eckart Laack | GERMANY | Hamburg (Hansestadt) | Hamburg |
| 428 | FSBI National Medical Research Center of Oncology named after N.N. Blokhin | Konstantin Laktionov | RUSSIA | Moscow | Moscow |
| 429 | ICON (LPRA) - Hungary | István Láng | HUNGARY | Budapest | Budapest |
| 430 | British Columbia Cancer Agency - Surrey | Christopher W. Lee | CANADA | British Columbia | Surrey |
| 431 | CHU Rennes - H？pital Pontchaillou | Hervé Lena | FRANCE | Ille-et-Vilaine | Rennes cedex 9 |
| 432 | N.N. Petrov National Medical Research Center of Oncology | Evgeny Levchenko | RUSSIA | St Petersburg | RUSSIA Evgeny Levchenko N.N. Petrov National Medical Research Center of Oncology Pesochny |
| 433 | Federal State Budgetary Institution “V.A. Almazov National Medical Research Center” of the Ministry of Health of the Russian Federation | Alla Lisyanskaya | RUSSIA | Saint Petersburg | Saint Petersburg |
| 434 | Hospital Universitari Sant Joan de Reus | Clara Beatriz Lucía Gozalvez | SPAIN | Tarragona | Reus |
| 435 | Centro Hospitalar Universitário de Lisboa Central - Hospital Curry Cabral | Ricardo Jorge Martins da Luz | PORTUGAL | Lisboa | Lisboa |
| 436 | High Technology Hospital MedCenter Ltd - Batumi | Tamta Makharadze | GEORGIA | Adjara | Batumi |
| 437 | Multiprofile Hospital for Active Treatment for Women's Health Nadezhda | Dimo Manov | BULGARIA | Sofia | Sofia |
| 438 | Budai Egészségk？zpont | Zsuzsanna (Zsuzsa) Márk | HUNGARY | Budapest | Budapest |
| 439 | H？pital Regional de Rimouski | Katerine Marquis | CANADA | Québec | Rimouski |
| 440 | LLC Todua Clinic | Tamar Melkadze | GEORGIA | Tbilisi | T'bilisi |
| 441 | Centro Hospitalar do Baixo Vouga | Juan Carlos Mellidez Barroso | PORTUGAL | Aveiro | Aveiro |
| 442 | University MultiProfile Hospital For Active Treatment Sofiamed | Velko Minchev | BULGARIA | Sofia | Sofia |
| 443 | Boise VA Medical Center | Paul Montgomery | UNITED STATES | Idaho | Boise |
| 444 | Pavlov First Saint Petersburg State Medical University | Igor Mosin | RUSSIA | Saint-Petersburg | Saint-Petersburg |
| 445 | Institut Català d'Oncologia - Hospital Duran i Reynals (ICO L'Hospitalet) | Ernesto Nadal Alforja | SPAIN | Barcelona | SPAIN Ernesto Nadal Alforja Institut Català d'Oncologia - Hospital Duran i Reynals (ICO L'Hospitalet) L’Hospitalet de Llobregat |
| 446 | Uniklinik K？ln | Lucia Nogova | GERMANY | Nordrhein-Westfalen | K？ln |
| 447 | Tuen Mun Hospital | Jonathan Shi Feng Nyaw | 中国香港 | New Territories | Tuen Mun |
| 448 | Bon Secours Health System - Cork | Deirdre O'Mahony | IRELAND | Cork | Cork |
| 449 | ？ukurova üniversitesi Balcal？ Hastanesi Sa？l？k Uygulama ve Ara？t？rma Merkezi | Ali O？ul | TURKEY | Adana | Adana |
| 450 | State Healthcare Institution Leningrad Regional Oncology Dispensary - Kuzmolovsky | Mikhail Osipov | RUSSIA | Leningradskaya Oblast | Kuzmolovsky |
| 451 | Cedars Cancer Centre | Scott Owen | CANADA | Quebec | Montreal |
| 452 | Istanbul Ac？badem University Medical School Altunizade Hospital | Basak Oyan Uluc | TURKEY | Istanbul | Istanbul |
| 453 | ？stanbul üniversitesi Cerrahpasa Tip Fakultesi Hastanesi | Mustafa Ozguroglu | TURKEY | Istanbul | Sisli |
| 454 | Erciyes Universitesi Tip Fakultesi - Hastaneleri | Metin Ozkan | TURKEY | Kayseri | Melikgazi |
| 455 | Istanbul Süreyyapa？a G？？üs Hastaliklari Ve G？？üs Cerrrahisi E？itim Ve Ara？tirma Hastanesi | Akin Ozturk | TURKEY | Istanbul | Maltepe |
| 456 | Theagenio Anti-Cancer Hospital of Thessaloniki | Pavlos Papakotoulas | GREECE | Thessaloniki | Thessaloniki |
| 457 | Centre Hospitalier Universitaire de Liège | Astrid Paulus | BELGIUM | Liège | Liege |
| 458 | Canberra Hospital | Geoffrey Peters | AUSTRALIA | Australian Capital Territory | Garran |
| 459 | Cliniques Universitaires Saint-Luc | Thierry Pieters | BELGIUM | Bruxelles-Capitale | Brussels |
| 460 | Békés Megyei K？zponti Kórház - Pándy Kálmán Tagkórház | Bela Piko | HUNGARY | Bekes | Gyula |
| 461 | Research Institute - Regional Clinical Hospital No. 1 named after Professor S.V. Ochapovsky | Igor Polyakov | RUSSIA | Krasnodar | Krasnodar |
| 462 | Wojewódzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w ？odzi | Piotr Potemski | POLAND | Lódzkie | ？ód？ |
| 463 | University General Hospital Attikon | Amanda Psyrri | GREECE | Attica | Athens |
| 464 | Cancer Centre of Southeastern Ontario | Andrew Robinson | CANADA | Ontario | Kingston |
| 465 | Complejo Hospitalario Universitario Insular Materno Infantil | Delvys Rodríguez-Abreu | SPAIN | Las Palmas | Las Palmas de Gran Canaria |
| 466 | R.S. McLaughlin Durham Regional Cancer Centre | Jeffrey Rothenstein | CANADA | Ontario | Oshawa |
| 467 | Ultrasound Clinic 4D | Daria Saenko | RUSSIA | Stavropol | Pyatigorsk |
| 468 | Lumi Research | Saleha Sajid | UNITED STATES | Texas | Sugarland |
| 469 | Hospital Universitario de La Princesa | Jose Miguel Sánchez Torres | SPAIN | Madrid | Madrid |
| 470 | H？pital Regional de Rimouski | Sophie Savary Bélanger | CANADA | Québec | Rimouski |
| 471 | Azienda Ospedaliero - Universitaria di Cagliari | Mario Scartozzi | ITALY | Upper Austria | Linz |
| 472 | Ko？ üniversitesi Hastanesi | Fatih Selcukbiricik | TURKEY | Zeytinburnu/？stanbul | ？stanbul |
| 473 | Mehmet Ali Nahit Sendur | T.C. Saglik Bakanligi Ankara Bilkent Sehi？r Hastanesi？ | TURKEY | Ankara | ？ankaya |
| 474 | Ba？kent üniversitesi Adana Dr Turgut Noyan Uygulama ve Ara？tirma Merkezi | Ahmet Sezer | TURKEY | Antalya | Adana |
| 475 | Unidade Local Saúde Alto Minho - Hospital de Santa Luzia | Ana Margarida Simas | PORTUGAL | Viana Do Castelo | Viana Do Castelo |
| 476 | Leids Universitair Medisch Centrum (LUMC) | Egbert Smit | NETHERLANDS | Noord-Holland | Amsterdam |
| 477 | Krajská Nemocnice Liberec | Marek Sochor | CZECH REPUBLIC | Liberec | Liberec |
| 478 | ？zel Egepol Hastanesi | Isil Somali | TURKEY | Izmir | Izmir |
| 479 | Somogy Megyei Kaposi Mór Oktató Kórház | éva Somogyiné Ezer | HUNGARY | Somogy | Kaposvár |
| 480 | University Multiprofile Hospital For Active Treatment Dr. Georgi Stranski EAD | Nataliya Petrova | BULGARIA | Pleven | Pleven |
| 481 | Klinikum der Johann Wolfgang Goethe-Universit？t | Jan Stratmann | GERMANY | Hessen | Frankfurt am Main |
| 482 | Universitair Ziekenhuis Gent | Veerle Surmont | BELGIUM | Oost-Vlaanderen | Gent |
| 483 | Jósa András Oktatókórház | Peter Szabó | HUNGARY | Szabolcs-Szatmár-Bereg | Nyíregyháza |
| 484 | Petz Aladár Egyetemi Oktató Kórház - Gy？r | Zsuzsanna Szalai | HUNGARY | Gyor-Moson-Sopron | Gy？r |
| 485 | Markusovszky Egyetemi Oktatókórház Szombathely | Barna Szima | HUNGARY | Vas | Szombathely |
| 486 | Ataturk Universitesi T？p Fakültesi | Salim Basol Tekin | TURKEY | Erzurum | Erzurum |
| 487 | General Hospital of Thessaloniki Papageorgiou | Eleni Timotheadou | GREECE | Central Macedonia | Nea Efkarpia |
| 488 | Curie Oncology - Farrer - 10-05 | Chee Keong Toh | SINGAPORE | Singapore | Singapore |
| 489 | Institut Universitaire de Cardiologie et de Pneumologie de Québec | Lise Tremblay | CANADA | Québec | Québec |
| 490 | Istanbul Bakirkoy Dr. Sadi Konuk Egitim Arastirma Hastanesi | Deniz Tural | TURKEY | Istanbul | Istanbul |
| 491 | Bezmialem Vak？f üniversitesi | Haci Turk | TURKEY | Istanbul | Fatih |
| 492 | New Vision University Hospital | Revaz Turmanidze | GEORGIA | Tbilisi | Tbilisi |
| 493 | Wojewódzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w ？odzi | Malgorzata U？ańska | POLAND | Lódzkie | ？ód？ |
| 494 | General Hospital of Kavala | Anastasios Vagionas | GREECE | Central Macedonia | Kavala |
| 495 | London Health Sciences Centre | Mark Vincent | CANADA | Ontario | London |
| 496 | Centre Hospitalier Régional et Universitaire de Besan？on - H？pital Jean-Minjoz | Virginie Westeel-Kaulek | FRANCE | Franche-Comte | Besan？on Cedex |
| 497 | Ottawa Hospital Research Institute | Paul Wheatley-Price | CANADA | Ontario | Ottawa |
| 498 | Advance Health Research Centre | Kevin Ka-Ming Wong | 中国香港 | Kowloon | Kowloon City |
| 499 | Alexandroupolis University General Hospital | Nikolaos Xenidis | GREECE | Eastern Macedonia and Thrace | Alexandroupoli |
| 500 | Gazi üniversitesi T？p Fakültesi | Ozan Yazici | TURKEY | Ankara | Yenimahalle |
| 501 | Ankara ？l Saglik Mudurlugu - Ankara Ataturk Sanatoryum Egitim Ve Arastirma Hastanesi | Ulku Yilmaz Turay | TURKEY | Ankara | Kecioeren |
| 502 | Institute for Pulmonary Diseases of Vojvodina | Bojan Zaric | SERBIA | Sremska Kamenica | Sremska Kamenica |
| 503 | Tbilisi Institute of Medicine | Mariam Zhvania | GEORGIA | Tbilisi | Tbilisi |
| 504 | Southlake Regional Health Centre | Labib Zibdawi | CANADA | Ontario | Newmarket |
| 505 | Szpital Specjalistyczny W Prabutach | Anna Lowczak | POLAND | Pomorskie | Prabuty |
五、伦理委员会信息
| 序号 | 名称 | 审查结论 | 批准日期/备案日期 |
|---|---|---|---|
| 1 | 上海胸科医院伦理委员会 | 同意 | 2022-05-11 |
| 2 | 上海胸科医院伦理委员会 | 同意 | 2022-08-03 |
| 3 | 上海胸科医院伦理委员会 | 同意 | 2022-09-07 |
| 4 | 上海胸科医院伦理委员会 | 同意 | 2023-05-31 |
六、试验状态信息
1、试验状态
进行中 （招募完成）
2、试验人数
| 目标入组人数 | 国内: 116 ； 国际: 登记人暂未填写该信息； |
|---|---|
| 已入组人数 | 国内: 91 ； 国际: 登记人暂未填写该信息； |
| 实际入组总人数 | 国内: 登记人暂未填写该信息； 国际: 登记人暂未填写该信息； |
3、受试者招募及试验完成日期
| 第一例受试者签署知情同意书日期 | 国内：2022-07-21； 国际：登记人暂未填写该信息； |
|---|---|
| 第一例受试者入组日期 | 国内：2022-07-30； 国际：登记人暂未填写该信息； |
| 试验完成日期 | 国内：登记人暂未填写该信息； 国际：登记人暂未填写该信息； |
七、临床试验结果摘要
| 序号 | 版本号 | 版本日期 |
|---|---|---|
| 暂未填写此信息 | ||
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